Difference between revisions of "Lupus erythematosus cell"

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'''Lupus erythematosus cell''', abbreviated ''LE cell'', is [[neutrophil]] that has engulfed an intact nucleus.<ref name=pmid26118732>{{Cite journal  | last1 = Magna | first1 = M. | last2 = Pisetsky | first2 = DS. | title = The Role of Cell Death in the Pathogenesis of SLE: Is Pyroptosis the Missing Link? | journal = Scand J Immunol | volume = 82 | issue = 3 | pages = 218-24 | month = Sep | year = 2015 | doi = 10.1111/sji.12335 | PMID = 26118732 }}</ref> This is seen in [[systemic lupus erythematosus]].
'''Lupus erythematosus cell''', abbreviated ''LE cell'', is [[neutrophil]] that has engulfed an intact nucleus.<ref name=pmid26118732>{{Cite journal  | last1 = Magna | first1 = M. | last2 = Pisetsky | first2 = DS. | title = The Role of Cell Death in the Pathogenesis of SLE: Is Pyroptosis the Missing Link? | journal = Scand J Immunol | volume = 82 | issue = 3 | pages = 218-24 | month = Sep | year = 2015 | doi = 10.1111/sji.12335 | PMID = 26118732 }}</ref> This is seen in [[systemic lupus erythematosus]].


It is also known as a '''LE body'''.


:AKA ''LE body''
==General==
*Initially described in [[bone marrow]].<ref>{{Cite journal  | last1 = HARGRAVES | first1 = MM. | last2 = RICHMOND | first2 = H. | last3 = MORTON | first3 = R. | title = Presentation of two bone marrow elements; the tart cell and the L.E. cell. | journal = Proc Staff Meet Mayo Clin | volume = 23 | issue = 2 | pages = 25-8 | month = Jan | year = 1948 | doi =  | PMID = 18921142 }}</ref>
*Initially described in [[bone marrow]].<ref name=pmid18921142>{{Cite journal  | last1 = HARGRAVES | first1 = MM. | last2 = RICHMOND | first2 = H. | last3 = MORTON | first3 = R. | title = Presentation of two bone marrow elements; the tart cell and the L.E. cell. | journal = Proc Staff Meet Mayo Clin | volume = 23 | issue = 2 | pages = 25-8 | month = Jan | year = 1948 | doi =  | PMID = 18921142 }}</ref>


==Microscopic==
==Microscopic==
Features:<ref name=pmid26118732/>
Features:<ref name=pmid26118732/>
*Neutrophil that has engulfed a blue body on H&E.
*Neutrophil that has engulfed a round blue body on H&E.


==See also==
==See also==

Revision as of 13:47, 9 May 2017

Lupus erythematosus cell, abbreviated LE cell, is neutrophil that has engulfed an intact nucleus.[1] This is seen in systemic lupus erythematosus.

It is also known as a LE body.

General

Microscopic

Features:[1]

  • Neutrophil that has engulfed a round blue body on H&E.

See also

References

  1. 1.0 1.1 Magna, M.; Pisetsky, DS. (Sep 2015). "The Role of Cell Death in the Pathogenesis of SLE: Is Pyroptosis the Missing Link?". Scand J Immunol 82 (3): 218-24. doi:10.1111/sji.12335. PMID 26118732.
  2. HARGRAVES, MM.; RICHMOND, H.; MORTON, R. (Jan 1948). "Presentation of two bone marrow elements; the tart cell and the L.E. cell.". Proc Staff Meet Mayo Clin 23 (2): 25-8. PMID 18921142.

[[Category:Stuff]