Difference between revisions of "Cytokeratin 19"
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'''Cytokeratin 19''', abbreviated '''CK19''', is a commonly available keratin [[immunostain]]. | '''Cytokeratin 19''', abbreviated '''CK19''', is a commonly available (low molecular weight) keratin [[immunostain]].<ref>{{Cite journal | last1 = Yui | first1 = T. | last2 = Ohmachi | first2 = T. | last3 = Matsuda | first3 = K. | last4 = Okamoto | first4 = M. | last5 = Taniyama | first5 = H. | title = Histochemical and immunohistochemical characterization of chordoma in ferrets. | journal = J Vet Med Sci | volume = 77 | issue = 4 | pages = 467-73 | month = Apr | year = 2015 | doi = 10.1292/jvms.14-0488 | PMID = 25648567 }}</ref> | ||
==Positive== | ==Positive== | ||
Revision as of 16:48, 9 May 2016
Cytokeratin 19, abbreviated CK19, is a commonly available (low molecular weight) keratin immunostain.[1]
Positive
- Thyroid.[2]
- Gastrointestinal tract.[2]
- Pancreas.[2]
- Cholangiocarcinoma.
- Salivary gland - marks luminal cells.
- Adamantinoma.
- Yolk sac tumour.[3]
- Breast carcinoma - common (~91%).[4]
- Lung adenocarcinoma (~95%).[4]
Negative
See also
References
- ↑ Yui, T.; Ohmachi, T.; Matsuda, K.; Okamoto, M.; Taniyama, H. (Apr 2015). "Histochemical and immunohistochemical characterization of chordoma in ferrets.". J Vet Med Sci 77 (4): 467-73. doi:10.1292/jvms.14-0488. PMID 25648567.
- ↑ 2.0 2.1 2.2 Jain, R.; Fischer, S.; Serra, S.; Chetty, R. (Jan 2010). "The use of Cytokeratin 19 (CK19) immunohistochemistry in lesions of the pancreas, gastrointestinal tract, and liver.". Appl Immunohistochem Mol Morphol 18 (1): 9-15. doi:10.1097/PAI.0b013e3181ad36ea. PMID 19956064.
- ↑ Bremmer, F.; Ströbel, P.; Hubertus, H.; Strecker, J.; Gaisa, N.; Strauß, A.; Schweyer, S.; Radzun, H-J. et al. (2015). [www.diagnosticpathology.org/content/10/1/7Cached "CK19 is a sensitive marker for yolk sac tumours of the testis."]. Diagnostic Pathology 10 (7). doi:10.1186/s13000-015-0243-y. www.diagnosticpathology.org/content/10/1/7Cached.
- ↑ 4.0 4.1 Masai, K.; Nakagawa, K.; Yoshida, A.; Sakurai, H.; Watanabe, S.; Asamura, H.; Tsuta, K. (Dec 2014). "Cytokeratin 19 expression in primary thoracic tumors and lymph node metastases.". Lung Cancer 86 (3): 318-23. doi:10.1016/j.lungcan.2014.09.018. PMID 25453845.