Difference between revisions of "Zenker's diverticulum"
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- Squamous mucosa with parakeratosis, mild chronic inflammation | - Squamous mucosa with parakeratosis, mild chronic inflammation | ||
and fibrosis; compatible with Zenker's diverticulum. | and fibrosis; compatible with Zenker's diverticulum. | ||
- NEGATIVE for dysplasia and NEGATIVE malignancy. | - NEGATIVE for dysplasia and NEGATIVE for malignancy. | ||
</pre> | </pre> | ||
Revision as of 17:18, 3 November 2015
Zenker's diverticulum is an outpouching of the mucosa and submucosa at the junction of the pharynx and esophagus.
It is also known as cricopharyngeal diverticulum, pharyngoesophageal diverticulum and hypopharyngeal diverticulum.[1]
General
- Clinical diagnosis.
- Benign.
- Squamous cell carcinoma may arise from it.[2][3]
- Uncommon.[4]
Clinical:[4]
Gross
Images
Zenker's diverticulum. (WC)
Microscopic
Features:[5]
- Squamous mucosa without nuclear atypia +/- parakeratosis.
DDx:
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Submitted as "Zenker's Diverticulum", Excision: - Squamous mucosa with parakeratosis, mild chronic inflammation and fibrosis; compatible with Zenker's diverticulum. - NEGATIVE for dysplasia and NEGATIVE for malignancy.
See also
References
- ↑ Nuño-Guzmán, CM.; García-Carrasco, D.; Haro, M.; Arróniz-Jáuregui, J.; Corona, JL.; Salcido, M.. "Zenker's Diverticulum: Diagnostic Approach and Surgical Management.". Case Rep Gastroenterol 8 (3): 346-52. doi:10.1159/000369130. PMID 25759630.
- ↑ Acar, T.; Savaş, R.; Kocaçelebi, K.; Ersöz, G. (Sep 2015). "Squamous cell carcinoma arising from a Zenker's diverticulum: contribution of FDG-PET/CT to the diagnosis.". Dis Esophagus. doi:10.1111/dote.12406. PMID 26415863.
- ↑ Wakita, A.; Motoyama, S.; Sato, Y.; Yoshino, K.; Sasaki, T.; Saito, H.; Minamiya, Y.; Ogawa, J. (2012). "Squamous cell carcinoma in an esophageal diverticulum below the aortic arch.". Int J Surg Case Rep 3 (11): 574-6. doi:10.1016/j.ijscr.2012.07.010. PMID 22940699.
- ↑ 4.0 4.1 Law, R.; Katzka, DA.; Baron, TH. (Nov 2014). "Zenker's Diverticulum.". Clin Gastroenterol Hepatol 12 (11): 1773-82; quiz e111-2. doi:10.1016/j.cgh.2013.09.016. PMID 24055983.
- ↑ 5.0 5.1 Singaporewalla, RM.; Mukherjee, JJ.; Thamboo, TP.; Cheah, WK. (Dec 2011). "Pharyngoesophageal diverticulum resembling a thyroid nodule on ultrasound.". Head Neck 33 (12): 1800-3. doi:10.1002/hed.21474. PMID 20665743.