Difference between revisions of "Diagnostic size cutoffs"

From Libre Pathology
Jump to navigation Jump to search
Line 22: Line 22:
| <2mm
| <2mm
| Low-grade [[ductal carcinoma in situ]]
| Low-grade [[ductal carcinoma in situ]]
| Different criterion for lesions in an [[intraductal papilloma]]
| Different criterion for lesions in an [[intraductal papilloma of the breast]]
|-
|-
| [[Atypical ductal hyperplasia]] in an [[intraductal papilloma]]
| [[Atypical ductal hyperplasia]] in an [[intraductal papilloma of the breast]]
| <3mm
| <3mm
| Low-grade [[ductal carcinoma in situ]] in an intraductal papilloma
| Low-grade [[ductal carcinoma in situ]] in an intraductal papilloma
| Different criterion for lesions '''not''' in an [[intraductal papilloma]]
| Different criterion for lesions '''not''' in an [[intraductal papilloma of the breast]]
|-
|-
| [[Pulmonary carcinoid tumourlet]]
| [[Pulmonary carcinoid tumourlet]]

Revision as of 21:19, 9 May 2016

Diagnostic size cutoffs are cutoffs which (in part) define a diagnosis and are seen in a number of places in pathology. They are usually somewhat arbitrary by their nature; however, they often make sense from a biologic big picture/management perspective. It doesn't make sense to treat ADH and low-grade DCIS the same, as their behaviour is different.

In pathology, size matters. With other things equal, in the context of how tumours are currently evaluated, big tumours usually do worse than small tumours.

Smaller lesion (precursor) Cutoff value (smaller lesion) Larger lesion (cancer) Notes
Papillary adenoma of the kidney <=0.5 cm Papillary renal cell carcinoma -
Atypical alveolar hyperplasia <5 mm[1] Adenocarcinoma in situ of the lung -
Atypical ductal hyperplasia <2mm Low-grade ductal carcinoma in situ Different criterion for lesions in an intraductal papilloma of the breast
Atypical ductal hyperplasia in an intraductal papilloma of the breast <3mm Low-grade ductal carcinoma in situ in an intraductal papilloma Different criterion for lesions not in an intraductal papilloma of the breast
Pulmonary carcinoid tumourlet <5 mm[2][3] Typical carcinoid lung tumour Typical carcinoid lung tumour not a cancer

See also

References

  1. Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 114. ISBN 978-0781765275.
  2. URL: http://pathhsw5m54.ucsf.edu/case7/image75.html. Accessed on: 23 January 2012.
  3. He, P.; Gu, X.; Wu, Q.; Lin, Y.; Gu, Y.; He, J. (Dec 2012). "Pulmonary carcinoid tumorlet without underlying lung disease: analysis of its relationship to fibrosis.". J Thorac Dis 4 (6): 655-8. doi:10.3978/j.issn.2072-1439.2012.06.11. PMID 23205296.