Difference between revisions of "Sarcomatoid urothelial carcinoma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Urothelial carcinoma with sarcomatoid differentiation -- intermed mag.jpg | |||
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| Caption = Sarcomatoid urothelial carcinoma. [[H&E stain]]. | |||
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| Micro = | |||
| Subtypes = (subtype of [[urothelial carcinoma]]) | |||
| LMDDx = [[sarcoma]], [[carcinosarcoma]] - esp. in women, other sarcomatoid carcinomas | |||
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| Gross = | |||
| Grossing = | |||
| Site = [[urothelium]] - [[urinary bladder]], [[ureter]], renal pelvis | |||
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| Prevalence = very rare | |||
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| Prognosis = poor | |||
| Other = | |||
| ClinDDx = | |||
| Tx = resection if feasible | |||
}} | |||
'''Sarcomatoid urothelial carcinoma''' (abbreviated '''sarcomatoid UC'''), also '''sarcomatoid urothelial cell carcinoma''' (abbreviated '''sarcomatoid UCC'''), is a rare variant of [[urothelial carcinoma]].<ref name=pmid26068625>{{Cite journal | last1 = Fatima | first1 = N. | last2 = Canter | first2 = DJ. | last3 = Carthon | first3 = BC. | last4 = Kucuk | first4 = O. | last5 = Master | first5 = VA. | last6 = Nieh | first6 = PT. | last7 = Ogan | first7 = K. | last8 = Osunkoya | first8 = AO. | title = Sarcomatoid urothelial carcinoma of the bladder: a contemporary clinicopathologic analysis of 37 cases. | journal = Can J Urol | volume = 22 | issue = 3 | pages = 7783-7 | month = Jun | year = 2015 | doi = | PMID = 26068625 }}</ref> | '''Sarcomatoid urothelial carcinoma''' (abbreviated '''sarcomatoid UC'''), also '''sarcomatoid urothelial cell carcinoma''' (abbreviated '''sarcomatoid UCC'''), is a rare variant of [[urothelial carcinoma]].<ref name=pmid26068625>{{Cite journal | last1 = Fatima | first1 = N. | last2 = Canter | first2 = DJ. | last3 = Carthon | first3 = BC. | last4 = Kucuk | first4 = O. | last5 = Master | first5 = VA. | last6 = Nieh | first6 = PT. | last7 = Ogan | first7 = K. | last8 = Osunkoya | first8 = AO. | title = Sarcomatoid urothelial carcinoma of the bladder: a contemporary clinicopathologic analysis of 37 cases. | journal = Can J Urol | volume = 22 | issue = 3 | pages = 7783-7 | month = Jun | year = 2015 | doi = | PMID = 26068625 }}</ref> | ||
Revision as of 06:22, 19 June 2015
| Sarcomatoid urothelial carcinoma | |
|---|---|
| Diagnosis in short | |
 Sarcomatoid urothelial carcinoma. H&E stain. | |
| Subtypes | (subtype of urothelial carcinoma) |
| LM DDx | sarcoma, carcinosarcoma - esp. in women, other sarcomatoid carcinomas |
| Site | urothelium - urinary bladder, ureter, renal pelvis |
|
| |
| Prevalence | very rare |
| Prognosis | poor |
| Treatment | resection if feasible |
Sarcomatoid urothelial carcinoma (abbreviated sarcomatoid UC), also sarcomatoid urothelial cell carcinoma (abbreviated sarcomatoid UCC), is a rare variant of urothelial carcinoma.[1]
General
Gross
Microscopic
Features:
- Urothelial carcinoma (classic or recognizable variant).
- Sarcomatoid differentiation - typically (undifferentiated) spindle cells.
- Approximately have 10% of heterologous elements,[1] e.g. chondrosarcomatous differentiation, osteosarcomatous differentiation.
DDx:
- Sarcoma - esp. those arising from the retroperitoneum.
Images
Sarcomatoid UCC - low mag.
Sarcomatoid UCC - intermed. mag.
Sarcomatoid UCC - high mag.
See also
References
- ↑ 1.0 1.1 1.2 1.3 Fatima, N.; Canter, DJ.; Carthon, BC.; Kucuk, O.; Master, VA.; Nieh, PT.; Ogan, K.; Osunkoya, AO. (Jun 2015). "Sarcomatoid urothelial carcinoma of the bladder: a contemporary clinicopathologic analysis of 37 cases.". Can J Urol 22 (3): 7783-7. PMID 26068625.
- ↑ Nicolas, MM.; Nazarullah, A.; Guo, CC. (Apr 2014). "Sarcomatoid urothelial carcinoma with chondrosarcomatous differentiation of the ureter: a case report.". Anal Quant Cytopathol Histpathol 36 (2): 111-6. PMID 24902363.
- ↑ Tian, X.; Zhao, J.; Wang, Y.; Xing, N. (Sep 2014). "Sarcomatoid carcinoma of the renal pelvis: A case report.". Oncol Lett 8 (3): 1208-1210. doi:10.3892/ol.2014.2240. PMID 25120689.