Difference between revisions of "Sarcomatoid urothelial carcinoma"
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==General== | ==General== | ||
*Rare.<ref name=pmid26068625/> | *Rare.<ref name=pmid26068625/> | ||
*Aggressive >55% dead within one year of presentation.<ref name=pmid26068625/> | |||
==Microscopic== | ==Microscopic== | ||
Features: | Features: | ||
#Urothelial carcinoma (classic or recognizable variant). | #Urothelial carcinoma (classic or recognizable variant). | ||
#Sarcomatoid differentiation. | #Sarcomatoid differentiation - typically (undifferentiated) spindle cells. | ||
#*Approximately have 10% of heterologous elements,<ref name=pmid26068625/> e.g. [[chondrosarcoma]]tous differentiation, [[osteosarcoma]]tous differentiation. | |||
DDx: | DDx: | ||
*[[Sarcoma]] - esp. those arising from the retroperitoneum. | *[[Sarcoma]] - esp. those arising from the retroperitoneum. | ||
===Images=== | |||
<gallery> | |||
Image: Urothelial carcinoma with sarcomatoid differentiation -- low mag.jpg | Sarcomatoid UCC - low mag. | |||
Image: Urothelial carcinoma with sarcomatoid differentiation -- intermed mag.jpg | Sarcomatoid UCC - intermed. mag. | |||
Image: Urothelial carcinoma with sarcomatoid differentiation -- high mag.jpg | Sarcomatoid UCC - high mag. | |||
</gallery> | |||
==See also== | ==See also== |
Revision as of 06:13, 19 June 2015
Sarcomatoid urothelial carcinoma (abbreviated sarcomatoid UC), also sarcomatoid urothelial cell carcinoma (abbreviated sarcomatoid UCC), is a rare variant of urothelial carcinoma.[1]
General
Microscopic
Features:
- Urothelial carcinoma (classic or recognizable variant).
- Sarcomatoid differentiation - typically (undifferentiated) spindle cells.
- Approximately have 10% of heterologous elements,[1] e.g. chondrosarcomatous differentiation, osteosarcomatous differentiation.
DDx:
- Sarcoma - esp. those arising from the retroperitoneum.