Difference between revisions of "Sarcomatoid urothelial carcinoma"

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==General==
==General==
*Rare.<ref name=pmid26068625/>
*Rare.<ref name=pmid26068625/>
*Aggressive >55% dead within one year of presentation.<ref name=pmid26068625/>


==Microscopic==
==Microscopic==
Features:
Features:
#Urothelial carcinoma (classic or recognizable variant).
#Urothelial carcinoma (classic or recognizable variant).
#Sarcomatoid differentiation.
#Sarcomatoid differentiation - typically (undifferentiated) spindle cells.
#*Approximately have 10% of heterologous elements,<ref name=pmid26068625/> e.g. [[chondrosarcoma]]tous differentiation, [[osteosarcoma]]tous differentiation.


DDx:
DDx:
*[[Sarcoma]] - esp. those arising from the retroperitoneum.
*[[Sarcoma]] - esp. those arising from the retroperitoneum.
===Images===
<gallery>
Image: Urothelial carcinoma with sarcomatoid differentiation -- low mag.jpg | Sarcomatoid UCC - low mag.
Image: Urothelial carcinoma with sarcomatoid differentiation -- intermed mag.jpg | Sarcomatoid UCC - intermed. mag.
Image: Urothelial carcinoma with sarcomatoid differentiation -- high mag.jpg | Sarcomatoid UCC - high mag.
</gallery>


==See also==
==See also==

Revision as of 06:13, 19 June 2015

Sarcomatoid urothelial carcinoma (abbreviated sarcomatoid UC), also sarcomatoid urothelial cell carcinoma (abbreviated sarcomatoid UCC), is a rare variant of urothelial carcinoma.[1]

General

  • Rare.[1]
  • Aggressive >55% dead within one year of presentation.[1]

Microscopic

Features:

  1. Urothelial carcinoma (classic or recognizable variant).
  2. Sarcomatoid differentiation - typically (undifferentiated) spindle cells.

DDx:

  • Sarcoma - esp. those arising from the retroperitoneum.

Images

See also

References

  1. 1.0 1.1 1.2 1.3 Fatima, N.; Canter, DJ.; Carthon, BC.; Kucuk, O.; Master, VA.; Nieh, PT.; Ogan, K.; Osunkoya, AO. (Jun 2015). "Sarcomatoid urothelial carcinoma of the bladder: a contemporary clinicopathologic analysis of 37 cases.". Can J Urol 22 (3): 7783-7. PMID 26068625.