Difference between revisions of "Renal leiomyoma"
Jump to navigation
Jump to search
| Line 11: | Line 11: | ||
DDx: | DDx: | ||
*[[Angiomyolipoma]] - typically contain adipose tissue. | *[[Angiomyolipoma]] - typically contain adipose tissue. | ||
*[[Leiomyosarcoma]]<ref name=pmid25526990>{{Cite journal | last1 = Fu | first1 = L. | last2 = Humphrey | first2 = PA. | last3 = Adeniran | first3 = AJ. | title = Renal Leiomyoma. | journal = J Urol | volume = | issue = | pages = | month = Dec | year = 2014 | doi = 10.1016/j.juro.2014.12.083 | PMID = 25526990 }}</ref> - typically have at least some of the following: nuclear atypia, mitosis, necrosis. | |||
==IHC== | ==IHC== | ||
Revision as of 22:55, 2 January 2015
Renal leiomyoma, also leiomyoma of the kidney, is a very rare benign kidney tumour.
General
- Rare - estimated to represent 0.3% of treated renal tumours.[1]
Microscopic
Features:
- Fasicular architecture.
- Spindle cells without significant atypia.
DDx:
- Angiomyolipoma - typically contain adipose tissue.
- Leiomyosarcoma[2] - typically have at least some of the following: nuclear atypia, mitosis, necrosis.
IHC
Features:[3]
- HMB-45 -ve.
- Desmin +ve.
- ER and PR +ve (6 of 9 cases:[3]).
See also
References
- ↑ Khetrapal, S.; Bhargava, A.; Jetley, S.; Rana, S.; Jairajpuri, Z. (Oct 2014). "Renal leiomyoma: an uncommon differential diagnosis of renal masses with a clinical relevance.". J Clin Diagn Res 8 (10): FD08-9. doi:10.7860/JCDR/2014/9434.4993. PMID 25478354.
- ↑ Fu, L.; Humphrey, PA.; Adeniran, AJ. (Dec 2014). "Renal Leiomyoma.". J Urol. doi:10.1016/j.juro.2014.12.083. PMID 25526990.
- ↑ 3.0 3.1 Patil, PA.; McKenney, JK.; Trpkov, K.; Hes, O.; Montironi, R.; Scarpelli, M.; Nesi, G.; Aron, M. et al. (Dec 2014). "Renal Leiomyoma: A Contemporary Multi-institution Study of an Infrequent and Frequently Misclassified Neoplasm.". Am J Surg Pathol. doi:10.1097/PAS.0000000000000354. PMID 25517956.