Difference between revisions of "Adenocarcinoma of the rete testis"

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DDx:
DDx:
*[[Adenomatous hyperplasia of the rete testis]].
*[[Adenomatous hyperplasia of the rete testis]] - may be a concurrent pathology.<ref name=pmid23800084>{{Cite journal  | last1 = Lin | first1 = XY. | last2 = Yu | first2 = JH. | last3 = Xu | first3 = HT. | last4 = Wang | first4 = L. | last5 = Fan | first5 = CF. | last6 = Liu | first6 = Y. | last7 = Wang | first7 = EH. | title = A case of adenocarcinoma of the rete testis accompanied by focal adenomatous hyperplasia. | journal = Diagn Pathol | volume = 8 | issue =  | pages = 105 | month =  | year = 2013 | doi = 10.1186/1746-1596-8-105 | PMID = 23800084 }}</ref>
*[[Metastatic]] carcinoma involving the testis - usually [[prostate carcinoma|prostate]], kidney, or colon.<ref name=pmid18769334>{{Cite journal  | last1 = Ulbright | first1 = TM. | last2 = Young | first2 = RH. | title = Metastatic carcinoma to the testis: a clinicopathologic analysis of 26 nonincidental cases with emphasis on deceptive features. | journal = Am J Surg Pathol | volume = 32 | issue = 11 | pages = 1683-93 | month = Nov | year = 2008 | doi = 10.1097/PAS.0b013e3181788516 | PMID = 18769334 }}</ref>
*[[Metastatic]] carcinoma involving the testis - usually [[prostate carcinoma|prostate]], kidney, or colon.<ref name=pmid18769334>{{Cite journal  | last1 = Ulbright | first1 = TM. | last2 = Young | first2 = RH. | title = Metastatic carcinoma to the testis: a clinicopathologic analysis of 26 nonincidental cases with emphasis on deceptive features. | journal = Am J Surg Pathol | volume = 32 | issue = 11 | pages = 1683-93 | month = Nov | year = 2008 | doi = 10.1097/PAS.0b013e3181788516 | PMID = 18769334 }}</ref>
*[[Sertoli cell tumour]].
*[[Sertoli cell tumour]].

Revision as of 06:56, 16 December 2014

Adenocarcinoma of the rete testis
Diagnosis in short

Adenocarcinoma of the rete testis. H&E stain.
LM DDx adenomatous hyperplasia of the rete testis, Sertoli cell tumour, metastasis
Gross orchiectomy grossing
Site testis - specifically rete testis

Prevalence extremely rare
Prognosis poor
Clin. DDx other testicular mass

Adenocarcinoma of the rete testis, also rete testis adenocarcinoma, is a very rare malignant tumour of the testis.

General

  • Extremely rare[1] - a few dozen cases in the world literature.
  • Typically older men (>60 years old), but reported in younger men with undescended testis.[1]
  • Possible association of diethylstilbestrol.[2]
  • Prognosis poor[3] - 3-year and 5-year disease-free survival approximately 50% and 15% respectively.[4]

Gross

  • Lesion of the testicular hilum.[1]

Microscopic

Features:

  • Adenocarcinoma:
    • Atypical columnar or cuboidal cells, often with cigar-shaped nuclei.
    • Tubular or papillary architecture.[2]
  • Transistion to normal appearing rete testis.[1]

DDx:

Images

www:

See also

References

  1. 1.0 1.1 1.2 1.3 1.4 Nochomovitz, LE.; Orenstein, JM. (Aug 1984). "Adenocarcinoma of the rete testis. Case report, ultrastructural observations, and clinicopathologic correlates.". Am J Surg Pathol 8 (8): 625-34. PMID 6465420.
  2. 2.0 2.1 Newbold, RR.; Bullock, BC.; McLachlan, JA. (Dec 1986). "Adenocarcinoma of the rete testis. Diethylstilbestrol-induced lesions of the mouse rete testis.". Am J Pathol 125 (3): 625-8. PMC 1888460. PMID 3799821. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1888460/.
  3. Sogni, F.; Monga, G.; Terrone, C.; Gontero, P. (2008). "Primary adenocarcinoma of the rete testis: diagnostic problems and therapeutic dilemmas.". Scand J Urol Nephrol 42 (1): 83-5. doi:10.1080/00365590701517608. PMID 17853037.
  4. Sánchez-Chapado, M.; Angulo, JC.; Haas, GP. (Oct 1995). "Adenocarcinoma of the rete testis.". Urology 46 (4): 468-75. doi:10.1016/S0090-4295(99)80257-X. PMID 7571213.
  5. Lin, XY.; Yu, JH.; Xu, HT.; Wang, L.; Fan, CF.; Liu, Y.; Wang, EH. (2013). "A case of adenocarcinoma of the rete testis accompanied by focal adenomatous hyperplasia.". Diagn Pathol 8: 105. doi:10.1186/1746-1596-8-105. PMID 23800084.
  6. Ulbright, TM.; Young, RH. (Nov 2008). "Metastatic carcinoma to the testis: a clinicopathologic analysis of 26 nonincidental cases with emphasis on deceptive features.". Am J Surg Pathol 32 (11): 1683-93. doi:10.1097/PAS.0b013e3181788516. PMID 18769334.
  7. Yang, Z.; Sheng, C.; Cao, L.; Wang, D.. "Adenocarcinoma of rete testis with widespread liver metastasis.". Can Urol Assoc J 7 (9-10): E654-6. doi:10.5489/cuaj.470. PMID 24409217.
  8. Tian, Y.; Yao, W.; Yang, L.; Wang, J.; Wazir, R.; Wang, K. (Feb 2014). "Primary adenocarcinoma of the rete testis: A case report and review of the literature.". Oncol Lett 7 (2): 455-457. doi:10.3892/ol.2013.1708. PMID 24396468.
  9. Wu, CA.; Chen, YH.; Man, KM.; Shen, JL.; Chen, WC. (2011). "Papillary adenocarcinoma of rete testis mimics inflammatory lump: a case report.". Case Rep Urol 2011: 857812. doi:10.1155/2011/857812. PMID 22606627.