Difference between revisions of "Neurocytoma"
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*Perinuclear clearing. | *Perinuclear clearing. | ||
*Well-defined cell borders. | *Well-defined cell borders. | ||
==IHC== | |||
*MIB-1: Usu. low. | |||
*Synapthophysin +ve. | |||
DDx: | DDx: | ||
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*[[Ganglioglioma]]. | *[[Ganglioglioma]]. | ||
*[[Ependymoma]]. | *[[Ependymoma]]. | ||
*[[Pilocytic astrocytoma]] (with predominantly oligo-like cell component). | |||
* Diffuse leptomeningeal gliomeuronal tumour. | |||
===Images=== | ===Images=== | ||
Revision as of 11:59, 9 July 2018
Neurocytoma is a rare neuropathology tumour.
General
- Rare.
Microscopic
Features:[1]
- Pineocytomatous/neurocytic rosette = irregular rosette with a large meshwork of fibers (neuropil) at the centre.[2]
- Similar to Homer-Wright rosette.
- Perinuclear clearing.
- Well-defined cell borders.
IHC
- MIB-1: Usu. low.
- Synapthophysin +ve.
DDx:
- Oligodendroglioma - do not have the characteristic rosettes.
- Ganglioglioma.
- Ependymoma.
- Pilocytic astrocytoma (with predominantly oligo-like cell component).
- Diffuse leptomeningeal gliomeuronal tumour.
Images
www:
- Neurocytoma (ouhsc.edu).
- Neurocytoma - several images (upmc.edu).
- Neurocytoma - cerebellar - several images (upmc.edu).
IHC
- Synaptophysin +ve.
- Most glial tumour -ve.[3]
See also
References
- ↑ URL: http://moon.ouhsc.edu/kfung/jty1/Composites/FNA0IE14-Neurocytoma-Micro.htm. Accessed on: 12 October 2011.
- ↑ Wippold FJ, Perry A (March 2006). "Neuropathology for the neuroradiologist: rosettes and pseudorosettes". AJNR Am J Neuroradiol 27 (3): 488–92. PMID 16551982.
- ↑ URL: http://path.upmc.edu/cases/case383/dx.html. Accessed on: 15 January 2012.