Difference between revisions of "Chondromyxoid fibroma"
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Features:<ref name=Ref_WMSP642>{{Ref WMSP|642}}</ref> | Features:<ref name=Ref_WMSP642>{{Ref WMSP|642}}</ref> | ||
*Spindle cells or stellate cells in a myxoid or chondroid stroma. | *Spindle cells or stellate cells in a myxoid or chondroid stroma. | ||
*Lobules with hypocellular centers and hypercellular peripheries. | |||
*Tumor lacks a true hyaline cartilage matrix | |||
*Lack of mitotic activity | |||
DDx: | DDx: | ||
Revision as of 11:14, 12 November 2014
Chondromyxoid fibroma is a rare benign chondro-osseous tumour typically found in the metaphysis of teenagers or young adults.
General
- Uncommon and benign.[1]
- Teenagers or young adults.
Gross
- Metaphyseal lesion - classic location.[2]
- Well-circumscribed.
- Fragments of white-grey rubbery tissue
Microscopic
Features:[3]
- Spindle cells or stellate cells in a myxoid or chondroid stroma.
- Lobules with hypocellular centers and hypercellular peripheries.
- Tumor lacks a true hyaline cartilage matrix
- Lack of mitotic activity
DDx:
- Phosphaturic mesenchymal tumour - case report.[4]
- Chondroblastoma
- Also produces immature cartilage but
- Epiphyseal location
- Chicken-wire calcifications
- Chondrosarcoma
- Mature hyaline cartilage formation
- Tumor permeation of the surrounding bone
- Mitotic activity
Images:
- Chondromyxoid fibroma - low mag. (webpathology.com).
- Chondromyxoid fibroma - high mag. (webpathology.com).
See also
References
- ↑ Bhamra, JS.; Al-Khateeb, H.; Dhinsa, BS.; Gikas, PD.; Tirabosco, R.; Pollock, RC.; Skinner, JA.; Aston, WJ. et al. (2014). "Chondromyxoid fibroma management: a single institution experience of 22 cases.". World J Surg Oncol 12: 283. doi:10.1186/1477-7819-12-283. PMID 25217119.
- ↑ Budny, AM.; Ismail, A.; Osher, L.. "Chondromyxoid fibroma.". J Foot Ankle Surg 47 (2): 153-9. doi:10.1053/j.jfas.2007.08.013. PMID 18312923.
- ↑ Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 642. ISBN 978-0781765275.
- ↑ Suryawanshi, P.; Agarwal, M.; Dhake, R.; Desai, S.; Rekhi, B.; Reddy, KB.; Jambhekar, NA. (Nov 2011). "Phosphaturic mesenchymal tumor with chondromyxoid fibroma-like feature: an unusual morphological appearance.". Skeletal Radiol 40 (11): 1481-5. doi:10.1007/s00256-011-1159-6. PMID 21533894.