Difference between revisions of "Smooth muscle tumour of uncertain malignant potential"
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==General== | ==General== | ||
*Like ''[[ASAP]]'' and ''[[ASCUS]]'' - a [[waffle diagnosis|waffle category]]... when one isn't sure it is a ''leiomyoma'' vs. ''leiomyosarcoma''. | *Like ''[[ASAP]]'' and ''[[ASCUS]]'' - a [[waffle diagnosis|waffle category]]... when one isn't sure it is a ''[[leiomyoma]]'' vs. ''[[leiomyosarcoma]]''. | ||
*Clinical behaviour in uterus: usually benign.<ref name=pmid19417585>{{cite journal |author=Ip PP, Cheung AN, Clement PB |title=Uterine smooth muscle tumors of uncertain malignant potential (STUMP): a clinicopathologic analysis of 16 cases |journal=Am. J. Surg. Pathol. |volume=33 |issue=7 |pages=992–1005 |year=2009 |month=July |pmid=19417585 |doi=10.1097/PAS.0b013e3181a02d1c |url=}}</ref> | *Clinical behaviour in uterus: usually benign.<ref name=pmid19417585>{{cite journal |author=Ip PP, Cheung AN, Clement PB |title=Uterine smooth muscle tumors of uncertain malignant potential (STUMP): a clinicopathologic analysis of 16 cases |journal=Am. J. Surg. Pathol. |volume=33 |issue=7 |pages=992–1005 |year=2009 |month=July |pmid=19417585 |doi=10.1097/PAS.0b013e3181a02d1c |url=}}</ref> | ||
*Can be subclassified into four groups - as per Stanford. | *Can be subclassified into four groups - as per Stanford. | ||
| Line 16: | Line 16: | ||
DDx: | DDx: | ||
*[[Uterine leiomyoma]]. | *[[Uterine leiomyoma]]. | ||
*[[ | *[[Leiomyosarcoma]]. | ||
**See ''[[uterine leiomyosarcoma]]'' for the uterine tumour. | |||
==IHC== | ==IHC== | ||
Revision as of 02:36, 23 October 2014
Smooth muscle tumour of uncertain malignant potential, abbreviated STUMP is smooth muscle lesion in which the behaviour (benign vs. malignant) cannot be ascertained with certainty.
General
- Like ASAP and ASCUS - a waffle category... when one isn't sure it is a leiomyoma vs. leiomyosarcoma.
- Clinical behaviour in uterus: usually benign.[1]
- Can be subclassified into four groups - as per Stanford.
- May be seen in the prostate gland.[2]
Management:
- Long-term follow-up.[1]
Microscopic
Features associated with recurrence:[1]
- Nuclear atypia.
DDx:
- Uterine leiomyoma.
- Leiomyosarcoma.
- See uterine leiomyosarcoma for the uterine tumour.
IHC
Features associated with recurrence:[1]
- p16 +ve.
- p53 +ve.
See also
References
- ↑ 1.0 1.1 1.2 1.3 Ip PP, Cheung AN, Clement PB (July 2009). "Uterine smooth muscle tumors of uncertain malignant potential (STUMP): a clinicopathologic analysis of 16 cases". Am. J. Surg. Pathol. 33 (7): 992–1005. doi:10.1097/PAS.0b013e3181a02d1c. PMID 19417585.
- ↑ Nagar, M.; Epstein, JI. (Jun 2011). "Epithelial proliferations in prostatic stromal tumors of uncertain malignant potential (STUMP).". Am J Surg Pathol 35 (6): 898-903. doi:10.1097/PAS.0b013e318214f2f2. PMID 21572264.