Difference between revisions of "Tubulocystic carcinoma of the kidney"
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==See also== | ==See also== | ||
*[[Clear cell papillary renal cell carcinoma]]. | *[[Clear cell papillary renal cell carcinoma]]. | ||
*[[Collecting duct carcinoma]]. | |||
*[[Kidney tumours]]. | *[[Kidney tumours]]. | ||
Revision as of 19:53, 3 November 2013
Tubulocystic carcinoma of the kidney, abbreviated TCCK, is a very rare kidney tumour.
It is also known as low-grade collecting duct carcinoma.[1]
General
- Not in the WHO classification of renal tumours - as of 2013.[2]
- Rare <1% - in a series of 615 cases.
- Males:Females ~ 7:1.[1]
- Prognosis - probably favourable.[1]
Gross
- Bubble wrap-like appearance - due to the cystic nature.[1]
Microscopic
Features:.[1]
- Cysts of variable size lined by a single layer of epithelium that has a:
- Cuboidal, flat, or hobnail morphology.
- Eosinophilic cytoplasm.
- Large nuclei with prominent nucleoli.
- +/-Fibrotic stroma.
DDx:
- Renal oncocytoma.
- Cystic nephroma/Mixed epithelial and stromal tumour.
- Multilocular cystic renal cell carcinoma.
IHC
Features:[2]
- CD10 +ve.
- RCC +ve.
- Vimentin +ve.
- AMACR +ve.
See also
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Amin, MB.; MacLennan, GT.; Gupta, R.; Grignon, D.; Paraf, F.; Vieillefond, A.; Paner, GP.; Stovsky, M. et al. (Mar 2009). "Tubulocystic carcinoma of the kidney: clinicopathologic analysis of 31 cases of a distinctive rare subtype of renal cell carcinoma.". Am J Surg Pathol 33 (3): 384-92. doi:10.1097/PAS.0b013e3181872d3f. PMID 19011562.
- ↑ 2.0 2.1 Alexiev, BA.; Drachenberg, CB. (May 2013). "Tubulocystic carcinoma of the kidney: a histologic, immunohistochemical, and ultrastructural study.". Virchows Arch 462 (5): 575-81. doi:10.1007/s00428-013-1398-0. PMID 23525677.