Difference between revisions of "Phosphaturic mesenchymal tumour"
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==Gross== | ==Gross== | ||
*Soft tissue ''or'' [[bone]].<ref name=pmid22532501>{{Cite journal | last1 = Jiang | first1 = Y. | last2 = Xia | first2 = WB. | last3 = Xing | first3 = XP. | last4 = Silva | first4 = BC. | last5 = Li | first5 = M. | last6 = Wang | first6 = O. | last7 = Zhang | first7 = HB. | last8 = Li | first8 = F. | last9 = Jing | first9 = HL. | title = Tumor-induced osteomalacia: an important cause of adult-onset hypophosphatemic osteomalacia in China: Report of 39 cases and review of the literature. | journal = J Bone Miner Res | volume = 27 | issue = 9 | pages = 1967-75 | month = Sep | year = 2012 | doi = 10.1002/jbmr.1642 | PMID = 22532501 }}</ref> | *Soft tissue ''or'' [[bone]].<ref name=pmid22532501>{{Cite journal | last1 = Jiang | first1 = Y. | last2 = Xia | first2 = WB. | last3 = Xing | first3 = XP. | last4 = Silva | first4 = BC. | last5 = Li | first5 = M. | last6 = Wang | first6 = O. | last7 = Zhang | first7 = HB. | last8 = Li | first8 = F. | last9 = Jing | first9 = HL. | title = Tumor-induced osteomalacia: an important cause of adult-onset hypophosphatemic osteomalacia in China: Report of 39 cases and review of the literature. | journal = J Bone Miner Res | volume = 27 | issue = 9 | pages = 1967-75 | month = Sep | year = 2012 | doi = 10.1002/jbmr.1642 | PMID = 22532501 }}</ref> | ||
*Often small - thus hard to identify.<ref name=pmid23868423>{{Cite journal | last1 = Ledford | first1 = CK. | last2 = Zelenski | first2 = NA. | last3 = Cardona | first3 = DM. | last4 = Brigman | first4 = BE. | last5 = Eward | first5 = WC. | title = The Phosphaturic Mesenchymal Tumor: Why is Definitive Diagnosis and Curative Surgery Often Delayed? | journal = Clin Orthop Relat Res | volume = | issue = | pages = | month = Jul | year = 2013 | doi = 10.1007/s11999-013-3178-1 | PMID = 23868423 }}</ref> | |||
==Microscopic== | ==Microscopic== | ||
Revision as of 11:35, 19 August 2013
| Phosphaturic mesenchymal tumour | |
|---|---|
| Diagnosis in short | |
| Site | soft tissue, bone |
|
| |
| Blood work | low serum phosphate |
Phosphaturic mesenchymal tumor is a rare tumour.
One type is the phosphaturic mesenchymal tumour, mixed connective tissue type, abbreviated PMTMCT.
General
- Extremely rare.
- Hypophosphatemia.[1]
- Most common cause of oncogenic osteomalacia (tumour-induced osteomalacia).[2]
Gross
Microscopic
Features:[2]
- Spindle cells without atypia in an eosinophilic matrix.
- Osteoclast-type giant cells.
- +/-Calcifications.
Image:
References
- ↑ Papierska, L.; Ćwikła, JB.; Misiorowski, W.; Rabijewski, M.; Sikora, K.; Wanyura, H. (2013). "Unusual case of phosphaturic mesenchymal tumor.". Pol Arch Med Wewn 123 (5): 255-6. PMID 23722193.
- ↑ 2.0 2.1 William, J.; Laskin, W.; Nayar, R.; De Frias, D. (Aug 2012). "Diagnosis of phosphaturic mesenchymal tumor (mixed connective tissue type) by cytopathology.". Diagn Cytopathol 40 Suppl 2: E109-13. doi:10.1002/dc.21647. PMID 22927293.
- ↑ Jiang, Y.; Xia, WB.; Xing, XP.; Silva, BC.; Li, M.; Wang, O.; Zhang, HB.; Li, F. et al. (Sep 2012). "Tumor-induced osteomalacia: an important cause of adult-onset hypophosphatemic osteomalacia in China: Report of 39 cases and review of the literature.". J Bone Miner Res 27 (9): 1967-75. doi:10.1002/jbmr.1642. PMID 22532501.
- ↑ Ledford, CK.; Zelenski, NA.; Cardona, DM.; Brigman, BE.; Eward, WC. (Jul 2013). "The Phosphaturic Mesenchymal Tumor: Why is Definitive Diagnosis and Curative Surgery Often Delayed?". Clin Orthop Relat Res. doi:10.1007/s11999-013-3178-1. PMID 23868423.
- ↑ Woo, VL.; Landesberg, R.; Imel, EA.; Singer, SR.; Folpe, AL.; Econs, MJ.; Kim, T.; Harik, LR. et al. (Dec 2009). "Phosphaturic mesenchymal tumor, mixed connective tissue variant, of the mandible: report of a case and review of the literature.". Oral Surg Oral Med Oral Pathol Oral Radiol Endod 108 (6): 925-32. doi:10.1016/j.tripleo.2009.07.005. PMID 19828339.