Difference between revisions of "Phosphaturic mesenchymal tumour"
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| Gross = | | Gross = | ||
| Grossing = | | Grossing = | ||
| Site = | | Site = [[soft tissue]], [[bone]] | ||
| Assdx = | | Assdx = | ||
| Syndromes = | | Syndromes = | ||
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==General== | ==General== | ||
*Extremely rare. | |||
*Hypophosphatemia.<ref name=pmid23722193>{{Cite journal | last1 = Papierska | first1 = L. | last2 = Ćwikła | first2 = JB. | last3 = Misiorowski | first3 = W. | last4 = Rabijewski | first4 = M. | last5 = Sikora | first5 = K. | last6 = Wanyura | first6 = H. | title = Unusual case of phosphaturic mesenchymal tumor. | journal = Pol Arch Med Wewn | volume = 123 | issue = 5 | pages = 255-6 | month = | year = 2013 | doi = | PMID = 23722193 }}</ref> | *Hypophosphatemia.<ref name=pmid23722193>{{Cite journal | last1 = Papierska | first1 = L. | last2 = Ćwikła | first2 = JB. | last3 = Misiorowski | first3 = W. | last4 = Rabijewski | first4 = M. | last5 = Sikora | first5 = K. | last6 = Wanyura | first6 = H. | title = Unusual case of phosphaturic mesenchymal tumor. | journal = Pol Arch Med Wewn | volume = 123 | issue = 5 | pages = 255-6 | month = | year = 2013 | doi = | PMID = 23722193 }}</ref> | ||
*Most common cause of ''oncogenic osteomalacia'' (tumour-induced osteomalacia).<ref name=pmid22927293>{{Cite journal | last1 = William | first1 = J. | last2 = Laskin | first2 = W. | last3 = Nayar | first3 = R. | last4 = De Frias | first4 = D. | title = Diagnosis of phosphaturic mesenchymal tumor (mixed connective tissue type) by cytopathology. | journal = Diagn Cytopathol | volume = 40 Suppl 2 | issue = | pages = E109-13 | month = Aug | year = 2012 | doi = 10.1002/dc.21647 | PMID = 22927293 }}</ref> | *Most common cause of ''oncogenic osteomalacia'' (tumour-induced osteomalacia).<ref name=pmid22927293>{{Cite journal | last1 = William | first1 = J. | last2 = Laskin | first2 = W. | last3 = Nayar | first3 = R. | last4 = De Frias | first4 = D. | title = Diagnosis of phosphaturic mesenchymal tumor (mixed connective tissue type) by cytopathology. | journal = Diagn Cytopathol | volume = 40 Suppl 2 | issue = | pages = E109-13 | month = Aug | year = 2012 | doi = 10.1002/dc.21647 | PMID = 22927293 }}</ref> | ||
==Gross== | |||
*Soft tissue ''or'' [[bone]].<ref name=pmid22532501>{{Cite journal | last1 = Jiang | first1 = Y. | last2 = Xia | first2 = WB. | last3 = Xing | first3 = XP. | last4 = Silva | first4 = BC. | last5 = Li | first5 = M. | last6 = Wang | first6 = O. | last7 = Zhang | first7 = HB. | last8 = Li | first8 = F. | last9 = Jing | first9 = HL. | title = Tumor-induced osteomalacia: an important cause of adult-onset hypophosphatemic osteomalacia in China: Report of 39 cases and review of the literature. | journal = J Bone Miner Res | volume = 27 | issue = 9 | pages = 1967-75 | month = Sep | year = 2012 | doi = 10.1002/jbmr.1642 | PMID = 22532501 }}</ref> | |||
==Microscopic== | ==Microscopic== | ||
Revision as of 11:18, 19 August 2013
| Phosphaturic mesenchymal tumour | |
|---|---|
| Diagnosis in short | |
| Site | soft tissue, bone |
|
| |
| Blood work | low serum phosphate |
Phosphaturic mesenchymal tumor is a rare tumour. It is also known as phosphaturic mesenchymal tumour, mixed connective tissue type, abbreviated PMTMCT.
General
- Extremely rare.
- Hypophosphatemia.[1]
- Most common cause of oncogenic osteomalacia (tumour-induced osteomalacia).[2]
Gross
Microscopic
Features:[2]
- Spindle cells without atypia in a fibrillary matrix.
- Osteoclast-type giant cells.
References
- ↑ Papierska, L.; Ćwikła, JB.; Misiorowski, W.; Rabijewski, M.; Sikora, K.; Wanyura, H. (2013). "Unusual case of phosphaturic mesenchymal tumor.". Pol Arch Med Wewn 123 (5): 255-6. PMID 23722193.
- ↑ 2.0 2.1 William, J.; Laskin, W.; Nayar, R.; De Frias, D. (Aug 2012). "Diagnosis of phosphaturic mesenchymal tumor (mixed connective tissue type) by cytopathology.". Diagn Cytopathol 40 Suppl 2: E109-13. doi:10.1002/dc.21647. PMID 22927293.
- ↑ Jiang, Y.; Xia, WB.; Xing, XP.; Silva, BC.; Li, M.; Wang, O.; Zhang, HB.; Li, F. et al. (Sep 2012). "Tumor-induced osteomalacia: an important cause of adult-onset hypophosphatemic osteomalacia in China: Report of 39 cases and review of the literature.". J Bone Miner Res 27 (9): 1967-75. doi:10.1002/jbmr.1642. PMID 22532501.