Difference between revisions of "Malignant histiocytosis"
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==Microscopic== | ==Microscopic== | ||
Features:<ref name=pmid17324277>{{Cite journal | last1 = Alexiev | first1 = BA. | last2 = Sailey | first2 = CJ. | last3 = McClure | first3 = SA. | last4 = Ord | first4 = RA. | last5 = Zhao | first5 = XF. | last6 = Papadimitriou | first6 = JC. | title = Primary histiocytic sarcoma arising in the head and neck with predominant spindle cell component. | journal = Diagn Pathol | volume = 2 | issue = | pages = 7 | month = | year = 2007 | doi = 10.1186/1746-1596-2-7 | PMID = 17324277 }}</ref> | Features:<ref name=pmid17324277>{{Cite journal | last1 = Alexiev | first1 = BA. | last2 = Sailey | first2 = CJ. | last3 = McClure | first3 = SA. | last4 = Ord | first4 = RA. | last5 = Zhao | first5 = XF. | last6 = Papadimitriou | first6 = JC. | title = Primary histiocytic sarcoma arising in the head and neck with predominant spindle cell component. | journal = Diagn Pathol | volume = 2 | issue = | pages = 7 | month = | year = 2007 | doi = 10.1186/1746-1596-2-7 | PMID = 17324277 | PMC = 1808440 | URL = http://www.diagnosticpathology.org/content/2/1/7 }}</ref> | ||
*Malignant histiocyte-like cells: | *Malignant histiocyte-like cells: | ||
**Nuclear atypia. | **Nuclear atypia. | ||
| Line 16: | Line 16: | ||
Image: | Image: | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808440/figure/F2/ HS (nih.gov)]. | *[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808440/figure/F2/ HS (nih.gov)]. | ||
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808440/figure/F3/ HS (nih.gov)]. | |||
==IHC== | ==IHC== | ||
Revision as of 13:04, 7 December 2012
Histiocytic sarcoma is a rare tumour.
General
- Uncommon.
Microscopic
Features:[1]
- Malignant histiocyte-like cells:
- Nuclear atypia.
- Abundant eosinophilic cytoplasm.
DDx:
- Pleomorphic undifferentiated sarcoma.
- Poorly differentiated carcinoma.
Image:
IHC
Features:[1]
- CD68 +ve.
See also
References
- ↑ 1.0 1.1 Alexiev, BA.; Sailey, CJ.; McClure, SA.; Ord, RA.; Zhao, XF.; Papadimitriou, JC. (2007). "Primary histiocytic sarcoma arising in the head and neck with predominant spindle cell component.". Diagn Pathol 2: 7. doi:10.1186/1746-1596-2-7. PMC 1808440. PMID 17324277. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1808440/.