Difference between revisions of "Plasma cell"
Jump to navigation
Jump to search
(create) |
m (fix sp.) |
||
| Line 4: | Line 4: | ||
Features: | Features: | ||
*Ovoid intermediate-small cell size ~ 12 micrometers: | *Ovoid intermediate-small cell size ~ 12 micrometers: | ||
**Cells slightly larger than [[red blood cell]]s and [[ | **Cells slightly larger than [[red blood cell]]s and [[neutrophil]]s. | ||
*Eccentric nucleus. | *Eccentric nucleus. | ||
**Nucleus usu. hugs the cell membrane. | **Nucleus usu. hugs the cell membrane. | ||
| Line 32: | Line 32: | ||
==See also== | ==See also== | ||
*[[Red blood cell]]. | *[[Red blood cell]]. | ||
*[[Neutrophil]]. | |||
*[[Plasma cell neoplasms]]. | |||
==References== | ==References== | ||
{{Reflist|1}} | {{Reflist|1}} | ||
[[Category: | [[Category:Basics]] | ||
Revision as of 03:00, 1 April 2012
The plasma cell is white blood cell that produces antibodies.
Microscopic
Features:
- Ovoid intermediate-small cell size ~ 12 micrometers:
- Cells slightly larger than red blood cells and neutrophils.
- Eccentric nucleus.
- Nucleus usu. hugs the cell membrane.
- "Clock-face" chromatin pattern.
- Small dots symmetrically rim the nuclear membrane - like the numbers on a clock.
- Abundant cytoplasm.
- Nucleus-to-cytoplasm ratio ~1:2
- Perinuclear hof (prominent Gogli apparatus).
- Pale perinuclear crescentic - may be up to the size of the nucleus in active plasma cells.
Images:
Neoplasia
Main article: Plasma cell neoplasms
Neoplasms derived from plasma cell are called plasma cell neoplasms.
IHC
Others:
- CD19 -ve.
- CD20 -ve
- CD56 -ve.
See also
References
- ↑ 1.0 1.1 Humphrey, Peter A; Dehner, Louis P; Pfeifer, John D (2008). The Washington Manual of Surgical Pathology (1st ed.). Lippincott Williams & Wilkins. pp. 554. ISBN 978-0781765275.