Difference between revisions of "Starvation"
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'''Starvation''' is due to lack of food, inability or lack of desire to eat. | '''Starvation''' is defined as deprivation of food for a lengthy period. Generally, it is due to lack of food, inability to eat or lack of desire to eat. It may includes people that can eat but cannot absorb the nutrients in their food. | ||
== | This article covers ''[[serous fat atrophy]]'' as it is classically seen in starvation. | ||
Causes of starvation | |||
=Starvation= | |||
===Causes of starvation=== | |||
*Psychiatric: | *Psychiatric: | ||
**Dementia. | **Dementia. | ||
| Line 16: | Line 18: | ||
**Disability/trauma - person falls and cannot get up, help not available. | **Disability/trauma - person falls and cannot get up, help not available. | ||
===Gross findings of starvation=== | |||
*Very low body mass index (BMI). | |||
*Soft brown/[[myxoid]] material replaces fat (serous fat atrophy). | |||
=Associated conditions= | |||
==Serous fat atrophy== | |||
===General=== | |||
Associations:<ref name=pmid19567708/> | |||
*Acute febrile states. | *Acute febrile states. | ||
*[[AIDS]]. | *[[AIDS]]. | ||
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*[[Lymphoma]]. | *[[Lymphoma]]. | ||
==Gross== | ===Gross=== | ||
Features:<ref name=pmid19567708>{{cite journal |author=Munfus DL, Menke DM |title=Case of severe serous fat atrophy |journal=Mayo Clin. Proc. |volume=84 |issue=7 |pages=570 |year=2009 |month=July |pmid=19567708 |pmc=2704126 |doi=10.4065/84.7.570 |url=http://www.mayoclinicproceedings.com/content/84/7/570.full}}</ref> | |||
*Soft brown/[[myxoid]] material replaces fat. | |||
==Microscopic== | ===Microscopic=== | ||
Features - serous fat atrophy: | Features - serous fat atrophy: | ||
*Globular cells ~3-4x the size of a [[RBC]] (24-32 micrometers) with: | *Globular cells ~3-4x the size of a [[RBC]] (24-32 micrometers) with: | ||
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*[http://commons.wikimedia.org/wiki/File:Fat_atrophy_-_very_high_mag.jpg Serous fat atrophy - very high mag. (WC)]. | *[http://commons.wikimedia.org/wiki/File:Fat_atrophy_-_very_high_mag.jpg Serous fat atrophy - very high mag. (WC)]. | ||
=See also= | |||
*[[Autopsy]]. | *[[Autopsy]]. | ||
=References= | |||
{{reflist| | {{reflist|2}} | ||
[[Category:Autopsy]] | [[Category:Autopsy]] | ||
[[Category:Weird stuff]] | [[Category:Weird stuff]] | ||
[[Category:Clinical]] | [[Category:Clinical]] | ||
Revision as of 15:07, 20 April 2012
Starvation is defined as deprivation of food for a lengthy period. Generally, it is due to lack of food, inability to eat or lack of desire to eat. It may includes people that can eat but cannot absorb the nutrients in their food.
This article covers serous fat atrophy as it is classically seen in starvation.
Starvation
Causes of starvation
- Psychiatric:
- Dementia.
- Anorexia nervosa.
- Disorder with delusions, e.g. schizophrenia, bipolar affective disorder - belief one is being poisoned.
- Organic disease:
- Malignancy, e.g. esophageal carcinoma.
- Causes of malabsorption.
- Vomiting.
- Other:
- Poverty.
- Young age (cannot feed themself).
- Disability/trauma - person falls and cannot get up, help not available.
Gross findings of starvation
- Very low body mass index (BMI).
- Soft brown/myxoid material replaces fat (serous fat atrophy).
Associated conditions
Serous fat atrophy
General
Associations:[1]
- Acute febrile states.
- AIDS.
- Alcoholism.
- Anorexia nervosa.
- Cachexia.
- Carcinomas.
- Chronic heart failure.
- Lymphoma.
Gross
Features:[1]
- Soft brown/myxoid material replaces fat.
Microscopic
Features - serous fat atrophy:
- Globular cells ~3-4x the size of a RBC (24-32 micrometers) with:
- Clear cytoplasm.
- One small peripheral nucleus without a nucleolus.
DDx:
Images:
See also
References
- ↑ 1.0 1.1 Munfus DL, Menke DM (July 2009). "Case of severe serous fat atrophy". Mayo Clin. Proc. 84 (7): 570. doi:10.4065/84.7.570. PMC 2704126. PMID 19567708. http://www.mayoclinicproceedings.com/content/84/7/570.full.
- ↑ Clarke, BE.; Brown, DJ.; Xipell, JM. (Jan 1983). "Gelatinous transformation of the bone marrow.". Pathology 15 (1): 85-8. PMID 6222282.