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Smooth muscle tumour of uncertain malignant potential (view source)
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'''Smooth muscle tumour of uncertain malignant potential''', abbreviated '''STUMP''' is smooth muscle lesion in which the behaviour (benign vs. malignant) cannot be ascertained with certainty. | |||
==General== | |||
*Like ''[[ASAP]]'' and ''[[ASCUS]]'' - a [[waffle diagnosis|waffle category]]... when one isn't sure it is a ''leiomyoma'' vs. ''leiomyosarcoma''. | |||
*Clinical behaviour in uterus: usually benign.<ref name=pmid19417585>{{cite journal |author=Ip PP, Cheung AN, Clement PB |title=Uterine smooth muscle tumors of uncertain malignant potential (STUMP): a clinicopathologic analysis of 16 cases |journal=Am. J. Surg. Pathol. |volume=33 |issue=7 |pages=992–1005 |year=2009 |month=July |pmid=19417585 |doi=10.1097/PAS.0b013e3181a02d1c |url=}}</ref> | |||
*Can be subclassified into four groups - as per Stanford. | |||
*May be seen in the [[prostate gland]].<ref name=pmid21572264>{{Cite journal | last1 = Nagar | first1 = M. | last2 = Epstein | first2 = JI. | title = Epithelial proliferations in prostatic stromal tumors of uncertain malignant potential (STUMP). | journal = Am J Surg Pathol | volume = 35 | issue = 6 | pages = 898-903 | month = Jun | year = 2011 | doi = 10.1097/PAS.0b013e318214f2f2 | PMID = 21572264 }}</ref> | |||
Management: | |||
*Long-term follow-up.<ref name=pmid19417585/> | |||
==Microscopic== | |||
Features associated with recurrence:<ref name=pmid19417585/> | |||
*Nuclear atypia. | |||
DDx: | |||
*[[Uterine leiomyoma]]. | |||
*[[Uterine leiomyosarcoma]]. | |||
==IHC== | |||
Features associated with recurrence:<ref name=pmid19417585/> | |||
*p16 +ve. | |||
*p53 +ve. | |||
==See also== | |||
*[[Uterine tumours]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Genitourinary pathology]] | |||
[[Category:Gynecologic pathology]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||