Difference between revisions of "Osteoid osteoma"

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#redirect [[Chondro-osseous tumours#Osteoid osteoma]]
'''Osteoid osteoma''', abbreviated '''OO''', is benign primary [[bone tumour]].
 
==General==
*Benign bone lesion.
 
Clinical:<ref name=Ref_Sternberg4_285>{{Ref Sternberg4|285}}</ref>
*Extremely painful.
**Relieved by [[NSAIDs]].
 
==Gross==
*Bone: femur > tibia > spine > elsewhere.<ref name=uthscsa>URL: http://radiology.uthscsa.edu/CME/ELTXT/OOT/skeletallocation.html http://radiology.uthscsa.edu/CME/ELTXT/OOT/skeletallocation.html]. Accessed on: 7 May 2012.</ref><ref name=radiologyassistant>URL: [http://www.radiologyassistant.nl/en/494e15cbf0d8d http://www.radiologyassistant.nl/en/494e15cbf0d8d]. Accessed on: 7 May 2012.</ref>
*Most common location (in bone): diaphysis.<ref name=uthscsa>URL: http://radiology.uthscsa.edu/CME/ELTXT/OOT/skeletallocation.html http://radiology.uthscsa.edu/CME/ELTXT/OOT/skeletallocation.html]. Accessed on: 7 May 2012.</ref>
 
Images:
*[http://njms2.umdnj.edu/tutorweb/casegifs/ostostgross.jpg Osteoid osteoma - gross (umdnj.edu)].<ref>URL: [http://njms2.umdnj.edu/tutorweb/gross.htm http://njms2.umdnj.edu/tutorweb/gross.htm]. Accessed on: 7 May 2012.</ref>
*[http://radiology.uthscsa.edu/CME/ELTXT/OOT/treatment.html Osteoid osteoma (uthscsa.edu)].
 
==Microscopic==
Features:<ref name=Ref_Sternberg4_285>{{Ref Sternberg4|285}}</ref>
*Anastomosing bony [[trabeculae]] with:
**Variable mineralization.
***Mineralization (calcium '''p'''hosphate) = '''p'''urple on [[H&E stain]].
**Osteoblasts rimming.
***Cells line-up at edge of bone.
 
Note:
*Histomorphologically near identical/indistinguishable from ''[[osteoblastoma]]'';<ref name=Ref_Sternberg4_286>{{Ref Sternberg4|286}}</ref> one needs some history to make the diagnosis.
 
===Images===
<gallery>
Image:Osteoid_osteoma_-_low_mag.jpg | Osteoid osteoma - low mag. (WC)
Image:Osteoid osteoma - intermed mag.jpg | Osteoid osteoma - intermed. mag. (WC)
Image:Osteoid_osteoma_-_high_mag.jpg | Osteoid osteoma - high mag. (WC)
Image:Osteoid osteoma - very high mag.jpg | Osteoid osteoma - very high mag. (WC)
</gallery>
www:
*[http://library.med.utah.edu/WebPath/COW/COW211.html Osteoid osteoma - CT scan (med.utah.edu)].
*[http://www.sciencephoto.com/images/imagePopUpDetails.html?pop=1&id=700030210&pviewid=&country=67&search=gschmeissners&matchtype=FUZZY Osteoid osteoma (sciencephoto.com)].
 
==Sign out==
<pre>
BONE, RIGHT FEMUR, EXCISION:
- OSTEOID OSTEOMA.
</pre>
 
===Micro===
The sections show anastomosing bony trabeculae with variable mineralization and osteoblastic rimming. Multinucleated osteoclasts are scattered through the lesion. Hemosiderin-laden macrophages are present. No osteocyte nuclear atypia is apparent. Mitotic activity is not apparent. The osteoid is not lace-like.
 
==See also==
*[[Chondro-osseous tumours]].
*[[Bone]].
 
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Chondro-osseous tumours]]
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