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Difference between revisions of "Breast pathology"
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→Normal histology: +lactational changes
m (→Nipple adenoma) |
(→Normal histology: +lactational changes) |
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#Calcifications - abnormality may be very small; typically 10 levels. | #Calcifications - abnormality may be very small; typically 10 levels. | ||
=Normal | =Normal= | ||
==Resting== | |||
*Glands -- normally has two cell layers (like the [[prostate]]). | *Glands -- normally has two cell layers (like the [[prostate]]). | ||
**Myoepithelial cells | **Myoepithelial cells | ||
| Line 71: | Line 72: | ||
Notes: | Notes: | ||
*The architecture is more important than the cytologic features in the diagnosis of malignancy in the breast;<ref>RS. 4 May 2010.</ref> low grade tumours have distorted architecture but normal/near normal cytology. | *The architecture is more important than the cytologic features in the diagnosis of malignancy in the breast;<ref>RS. 4 May 2010.</ref> low grade tumours have distorted architecture but normal/near normal cytology. | ||
==Lactational changes== | |||
===General=== | |||
*May be present focally in non-pregnant females. | |||
===Microscopic=== | |||
Features:<ref>URL: [http://flylib.com/books/en/2.953.1.9/1/ http://flylib.com/books/en/2.953.1.9/1/]. Accessed on: 6 August 2011.</ref> | |||
*Glands dilated. | |||
*Increased number of lobules. | |||
**Relative decrease in intralobular and extralobular stroma. | |||
*Luminal cells enlarged. | |||
**Vacuolated cytoplasm. | |||
**Hobnail morphology - hang into the lumen. | |||
*Myoepithelial cells indistinct - after second semester. | |||
Images: | |||
*[http://www.gfmer.ch/selected_images_v2/detail_list.php?cat1=2&cat2=9&cat3=0&cat4=3&stype=n Lactational changes (gfmer.ch)]. | |||
=Where to start= | =Where to start= | ||