Difference between revisions of "Adrenal gland"

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===Microscopic===
===Microscopic===
Various criteria exist for this diagnosis.  The most widely used is the ''Weiss criteria'', which is a big long clunker.
Various criteria exist for this diagnosis.  The most widely used is the ''Weiss criteria'', which is a big long clunker.
Image:
*[http://commons.wikimedia.org/wiki/File:Adrnal_cortical_carcinoma.JPG ACC (AFIP/WC)].
Notes:
*Tumour may contain fat.<ref name=pmid15688105>{{cite journal |author=Heye S, Woestenborghs H, Van Kerkhove F, Oyen R |title=Adrenocortical carcinoma with fat inclusion: case report |journal=Abdom Imaging |volume=30 |issue=5 |pages=641–3 |year=2005 |pmid=15688105 |doi=10.1007/s00261-004-0281-5 |url=}}</ref>
====Adult====
====Adult====
=====Weiss criteria=====
=====Weiss criteria=====
Line 160: Line 167:
=====Volante criteria=====
=====Volante criteria=====
There is a simplified set of criteria by ''Volante et al.'' - that is not widely used:<ref name=pmid19912359>{{cite journal |author=Volante M, Bollito E, Sperone P, ''et al.'' |title=Clinicopathological study of a series of 92 adrenocortical carcinomas: from a proposal of simplified diagnostic algorithm to prognostic stratification |journal=Histopathology |volume=55 |issue=5 |pages=535–43 |year=2009 |month=November |pmid=19912359 |doi=10.1111/j.1365-2559.2009.03423.x |url=}}</ref>
There is a simplified set of criteria by ''Volante et al.'' - that is not widely used:<ref name=pmid19912359>{{cite journal |author=Volante M, Bollito E, Sperone P, ''et al.'' |title=Clinicopathological study of a series of 92 adrenocortical carcinomas: from a proposal of simplified diagnostic algorithm to prognostic stratification |journal=Histopathology |volume=55 |issue=5 |pages=535–43 |year=2009 |month=November |pmid=19912359 |doi=10.1111/j.1365-2559.2009.03423.x |url=}}</ref>
#Reticular network disruption (with reticulin staining).
*Reticular network disruption (with reticulin staining).
#One of the three following:
*One of the three following:
##Abundant mitoses >5/50 high-power fields - definition suffers from [[HPFitis]].
*#Abundant mitoses >5/50 high-power fields - definition suffers from [[HPFitis]].
##Necrosis.  
*#Necrosis.  
##Vascular invasion.
*#Vascular invasion.
 
Image:
*[http://commons.wikimedia.org/wiki/File:Adrnal_cortical_carcinoma.JPG ACC (AFIP/WC)].
 
Notes:
*Tumour may contain fat.<ref name=pmid15688105>{{cite journal |author=Heye S, Woestenborghs H, Van Kerkhove F, Oyen R |title=Adrenocortical carcinoma with fat inclusion: case report |journal=Abdom Imaging |volume=30 |issue=5 |pages=641–3 |year=2005 |pmid=15688105 |doi=10.1007/s00261-004-0281-5 |url=}}</ref>


====Pediatric====
====Pediatric====
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