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m (→Microscopic) |
m (→Microscopic) |
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#Neurofibrillary tangles. | #Neurofibrillary tangles. | ||
#*Consists of ''tau''. | #*Consists of ''tau''. | ||
#*Location: hippocampus, cerebral cortex | #*Location: hippocampus, cerebral cortex, hypothalamus. | ||
#*Images: [http://www.pakmed.net/academic/age/alz/plaques_tanglesBorder.jpg tangles - schematic (pakmed.net)]<ref name=pakmednet>URL: [http://www.pakmed.net/academic/age/alz/alz030.htm http://www.pakmed.net/academic/age/alz/alz030.htm]. Accessed on: 12 November 2010.</ref>, [http://faculty.washington.edu/alexbert/MEDEX/Fall/adtangle.jpg tangle (washington.edu)].<ref name=alexbert>URL: [http://faculty.washington.edu/alexbert/MEDEX/Fall/NeuroPath_Obj.htm http://faculty.washington.edu/alexbert/MEDEX/Fall/NeuroPath_Obj.htm]. Accessed on: 13 November 2010.</ref> | #*Images: [http://www.pakmed.net/academic/age/alz/plaques_tanglesBorder.jpg tangles - schematic (pakmed.net)]<ref name=pakmednet>URL: [http://www.pakmed.net/academic/age/alz/alz030.htm http://www.pakmed.net/academic/age/alz/alz030.htm]. Accessed on: 12 November 2010.</ref>, [http://faculty.washington.edu/alexbert/MEDEX/Fall/adtangle.jpg tangle (washington.edu)].<ref name=alexbert>URL: [http://faculty.washington.edu/alexbert/MEDEX/Fall/NeuroPath_Obj.htm http://faculty.washington.edu/alexbert/MEDEX/Fall/NeuroPath_Obj.htm]. Accessed on: 13 November 2010.</ref> | ||
#Senile plaques. | #Senile plaques. | ||
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#*#*Consists of Abeta amyloid | #*#*Consists of Abeta amyloid | ||
#*#Neurites - swollen axons. | #*#Neurites - swollen axons. | ||
#*Considered to be more specific for Alzheimer's than NF tangles. | |||
Notes: | Notes: | ||
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*Tau: | *Tau: | ||
**Important in microtubule assembly. | **Important in microtubule assembly. | ||
====Staging==== | |||
Senile plaque grouped into one of three stages. | |||
==Lewy body diseases== | ==Lewy body diseases== |
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