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** Perivascular. | ** Perivascular. | ||
* Enlarged stromal fibroblasts. | * Enlarged stromal fibroblasts. | ||
==Microglandular adenosis== | |||
===General=== | |||
*Controversial thingy. | |||
===Microscopic=== | |||
Features:<ref name=uscap_mga>URL: [http://www.uscap.org/site~/iap2006/slides08-4v.htm http://www.uscap.org/site~/iap2006/slides08-4v.htm]. Accessed on: 18 May 2011.</ref> | |||
*Round glands lined by a single layer of cells. | |||
*May extend into fat. | |||
DDx: | |||
*Tubular carcinoma - has apical snouts, desmoplasia among other things; see page by ''Collins''.<ref name=uscap_mga>URL: [http://www.uscap.org/site~/iap2006/slides08-4v.htm http://www.uscap.org/site~/iap2006/slides08-4v.htm]. Accessed on: 18 May 2011.</ref> | |||
*Sclerosing adenosis. | |||
Image: | |||
*[http://www.surgicalpathologyatlas.com/glfusion/mediagallery/media.php?f=1&s=20080802171452955&i=0&p=0 Microglandular adenosis (surgical pathologyatlas.com)]. | |||
===IHC=== | |||
Features:<ref name=pmid8821958>{{Cite journal | last1 = Joshi | first1 = MG. | last2 = Lee | first2 = AK. | last3 = Pedersen | first3 = CA. | last4 = Schnitt | first4 = S. | last5 = Camus | first5 = MG. | last6 = Hughes | first6 = KS. | title = The role of immunocytochemical markers in the differential diagnosis of proliferative and neoplastic lesions of the breast. | journal = Mod Pathol | volume = 9 | issue = 1 | pages = 57-62 | month = Jan | year = 1996 | doi = | PMID = 8821958 }}</ref> | |||
*S100 +ve. | |||
*34BE12 +ve -- focal! | |||
=See also= | =See also= |
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