Difference between revisions of "Hepatocellular carcinoma"

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Hepatocellular carcinoma with acini.

Fibrous bands dissect hepatocyte nodules, mostly hepatoma

Fibrous bands dissect hepatocyte nodules, mostly hepatoma (Row 1 Left 20X). The fibrous band on right bears proliferating bile ductules; acinar arrangement on left shows holes much larger than canaliculi (Row 1 Right 100X). The tumor has cancerous nuclei; note the bile which makes for absolute diagnostic certainty [arrow] (Row 2 Left 400X). Noncancerous hepatocytes on left can be compared with tumor cells on right. Note increased nuclear crowding & a subtle increment in cytoplasmic basophilia in tumor (Row 2 Right 400X).

(Row 1 Left 20X). The fibrous band on right bears proliferating bile ductules; acinar arrangement on left shows holes much larger than canaliculi (Row 1 Right 100X). The tumor has cancerous nuclei; note the bile which makes for absolute diagnostic certainty [arrow] (Row 2 Left 400X). Noncancerous hepatocytes on left can be compared with tumor cells on right. Note increased nuclear crowding & a subtle increment in cytoplasmic basophilia in tumor (Row 2 Right 400X).

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[[File:1 steatohep HCC 6 680x512px.tif|Fragments of tumor at low power mimic normal hepatocyte groups without triads (Row 1 Left 20X).]]

[[File:2 steatohep HCC 6 680x512px.tif|Vacuoles, mostly small, occasionally become large enough to warrant “macrovesicular” [green arrows]. Note Mallory hyalin [red arrows] (Row 1 Right 400X).]]

<br>

[[File:3 steatohep HCC 6 680x512px.tif|Chronic inflammatory cells bound some cancer cells (Row 2 Left 400X).]]

[[File:4 steatohep HCC 6 680x512px.tif|Nuclear inclusions are occasionally prominent [arrows] (Row 2 Right 400X).]]

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Hepatocellular carcinoma, steatohepatitic variant.

Fragments of tumor at low power mimic normal hepatocyte groups without portal triads (Row 1 Left 20X). Vacuoles, mostly small, occasionally become large enough to warrant the term “macrovesicular” [green arrows]. Note Mallory hyalin [red arrows] (Row 1 Right 400X). Chronic inflammatory cells bound some cancer cells (Row 2 Left 400X). Nuclear inclusions [arrows] are occasionally prominent [arrows] (Row 2 Right 400X).

===Fibrolamellar hepatocellular carcinoma===

Difference between revisions of "Hepatocellular carcinoma"

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@@ Line 116: / Line 116: @@
 |}
 Hepatocellular carcinoma with acini.
-Fibrous bands dissect hepatocyte nodules, mostly hepatoma
+Fibrous bands dissect hepatocyte nodules, mostly hepatoma (Row 1 Left 20X). The fibrous band on right bears proliferating bile ductules; acinar arrangement on left shows holes much larger than canaliculi (Row 1 Right 100X). The tumor has cancerous nuclei; note the bile which makes for absolute diagnostic certainty [arrow] (Row 2 Left 400X). Noncancerous hepatocytes on left can be compared with tumor cells on right. Note increased nuclear crowding & a subtle increment in cytoplasmic basophilia in tumor   (Row 2 Right 400X).
-(Row 1 Left 20X). The fibrous band on right bears proliferating bile ductules; acinar arrangement on left shows holes much larger than canaliculi (Row 1 Right 100X). The tumor has cancerous nuclei; note the bile which makes for absolute diagnostic certainty [arrow] (Row 2 Left 400X). Noncancerous hepatocytes on left can be compared with tumor cells on right. Note increased nuclear crowding & a subtle increment in cytoplasmic basophilia in tumor   (Row 2 Right 400X).
+{|
+[[File:1 steatohep HCC 6 680x512px.tif|Fragments of tumor at low power mimic normal hepatocyte groups without triads (Row 1 Left 20X).]]
+[[File:2 steatohep HCC 6 680x512px.tif|Vacuoles, mostly small, occasionally become large enough to warrant “macrovesicular” [green arrows]. Note Mallory hyalin [red arrows] (Row 1 Right 400X).]]
+<br>
+[[File:3 steatohep HCC 6 680x512px.tif|Chronic inflammatory cells bound some cancer cells (Row 2 Left 400X).]]
+[[File:4 steatohep HCC 6 680x512px.tif|Nuclear inclusions are occasionally prominent [arrows] (Row 2 Right 400X).]]
+|}
+Hepatocellular carcinoma, steatohepatitic variant.
+Fragments of tumor at low power mimic normal hepatocyte groups without portal triads (Row 1 Left 20X). Vacuoles, mostly small, occasionally become large enough to warrant the term “macrovesicular” [green arrows]. Note Mallory hyalin [red arrows] (Row 1 Right 400X). Chronic inflammatory cells bound some cancer cells (Row 2 Left 400X). Nuclear inclusions [arrows] are occasionally prominent [arrows] (Row 2 Right 400X).
 ===Fibrolamellar hepatocellular carcinoma===