Difference between revisions of "Herpes esophagitis"

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#redirect [[Esophagus#Herpes_esophagitis]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Herpes_esophagitis_-_very_high_mag.jpg
| Width      =
| Caption    = Herpes esophagitis
| Synonyms  =
| Micro      = nuclear moulding, multinucleation, margination of chromatin
| Subtypes  =
| LMDDx      =
| Stains    =
| IHC        = HSV-1 +ve
| EM        =
| Molecular  =
| IF        =
| Gross      =
| Grossing  =
| Staging    =
| Site      = [[esophagus]]
| Assdx      =
| Syndromes  =
| Clinicalhx = usually immune deficient
| Signs      =
| Symptoms  =
| Prevalence = rare
| Bloodwork  =
| Rads      =
| Endoscopy  = punched-out ulcers with brown/red edge
| Prognosis  =
| Other      =
| ClinDDx    =
| Tx        =
}}
'''Herpes esophagitis''' is an inflammation of the [[esophagus]] due to [[herpes simplex virus]].
 
==General==
*Usually immunodeficient.<ref name=pmid23082710>{{Cite journal  | last1 = Monsanto | first1 = P. | last2 = Almeida | first2 = N. | last3 = Cipriano | first3 = MA. | last4 = Gouveia | first4 = H. | last5 = Sofia | first5 = C. | title = Concomitant herpetic and eosinophilic esophagitis--a causality dilemma. | journal = Acta Gastroenterol Belg | volume = 75 | issue = 3 | pages = 361-3 | month = Sep | year = 2012 | doi =  | PMID = 23082710 }}</ref>
 
Etiology:
*[[Herpes simplex virus]].
 
==Gross/endoscopic==
Features:
*Ulcers with a "punched-out" appearance with a brown/red edge.
 
===Images===
<gallery>
Image:Herpes_esophagitis.JPG | Herpes esophagitis - endoscopy. (WC)
</gallery>
www:
*[http://library.med.utah.edu/WebPath/GIHTML/GI003.html Herpes esophagitis - gross (utah.edu)].
*[http://www.gastrohep.com/images/image.asp?id=648 Herpes esophagitis - endoscopy (gastrohep.com)].
 
==Microscopic==
Features (3 Ms):
*'''M'''oulding.
*'''M'''ultinucleation.
*'''M'''argination of chromatin.
 
===Images===
<gallery>
Image:Herpes_esophagitis_-_very_high_mag.jpg | HSV esophagitis - very high mag. (WC/Nephron)
Image:Herpes_esophagitis_-_intermed_mag.jpg | HSV esophagitis - intermed. mag. (WC/Nephron)
</gallery>
 
==IHC==
*HSV-1 +ve.<ref name=pmid20616659>{{Cite journal  | last1 = Canalejo Castrillero | first1 = E. | last2 = García Durán | first2 = F. | last3 = Cabello | first3 = N. | last4 = García Martínez | first4 = J. | title = Herpes esophagitis in healthy adults and adolescents: report of 3 cases and review of the literature. | journal = Medicine (Baltimore) | volume = 89 | issue = 4 | pages = 204-10 | month = Jul | year = 2010 | doi = 10.1097/MD.0b013e3181e949ed | PMID = 20616659 }}</ref>
**Occasionally HSV-2 +ve.
 
==See also==
*[[Esophagus]].
 
==References==
{{Reflist|2}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]
[[Category:Esophagus]]

Latest revision as of 21:28, 6 March 2025

Herpes esophagitis is an inflammation of the esophagus due to herpes simplex virus.

Herpes esophagitis
Diagnosis in short

Herpes esophagitis

LM nuclear moulding, multinucleation, margination of chromatin
IHC HSV-1 +ve
Site esophagus

Clinical history usually immune deficient
Prevalence rare
Endoscopy punched-out ulcers with brown/red edge

General

  • Usually immunodeficient.[1]

Etiology:

Gross/endoscopic

Features:

  • Ulcers with a "punched-out" appearance with a brown/red edge.

Images

www:

Microscopic

Features (3 Ms):

  • Moulding.
  • Multinucleation.
  • Margination of chromatin.

Images

IHC

  • HSV-1 +ve.[2]
    • Occasionally HSV-2 +ve.

See also

References

  1. Monsanto, P.; Almeida, N.; Cipriano, MA.; Gouveia, H.; Sofia, C. (Sep 2012). "Concomitant herpetic and eosinophilic esophagitis--a causality dilemma.". Acta Gastroenterol Belg 75 (3): 361-3. PMID 23082710.
  2. Canalejo Castrillero, E.; García Durán, F.; Cabello, N.; García Martínez, J. (Jul 2010). "Herpes esophagitis in healthy adults and adolescents: report of 3 cases and review of the literature.". Medicine (Baltimore) 89 (4): 204-10. doi:10.1097/MD.0b013e3181e949ed. PMID 20616659.