Angiokeratoma: Difference between revisions
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Angiokeratoma_-_low_mag.jpg | |||
| Width = | |||
| Caption = Angiokeratoma. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = ectatic superficial dermal vessels with overlying hyperkeratosis (thick stratum corneum); should have "epidermal collarette" (vascular space is surrounded by epidermis on three sides) | |||
| Subtypes = | |||
| LMDDx = [[venous lake]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[skin]] | |||
| Assdx = | |||
| Syndromes = [[Fabry disease]] | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = [[melanocytic lesions]], other [[vascular lesions]] | |||
| Tx = | |||
}} | |||
'''Angiokeratoma''' is a benign [[skin]] lesion. | |||
==General== | |||
*Rare. | |||
*May be seen in the context of [[Fabry disease]].<ref name=pmid16403380/> | |||
Notes: | |||
*Shouldn't be confused with ''[[angiofibroma]]'' which is associated [[tuberous sclerosis]]. | |||
==Gross== | |||
*Dark lesions. | |||
Clinical DDx: | |||
*[[Melanocytic lesions]]. | |||
===Images=== | |||
<gallery> | |||
Image:Angiokeratoma_of_the_Scrotum_7.jpg | Angiokeratoma. (WC) | |||
</gallery> | |||
==Microscopic== | |||
Features:<ref name=pmid16403380>{{Cite journal | last1 = Karen | first1 = JK. | last2 = Hale | first2 = EK. | last3 = Ma | first3 = L. | title = Angiokeratoma corporis diffusum (Fabry disease). | journal = Dermatol Online J | volume = 11 | issue = 4 | pages = 8 | month = | year = 2005 | doi = | PMID = 16403380 }}</ref> | |||
#Ectatic superficial dermal vessels. | |||
#Overlying hyperkeratosis (thick stratum corneum). | |||
*Should have "epidermal collarette".<ref name=Ref_Derm548>{{Ref Derm|548}}</ref> | |||
**Vascular space surrounded by epidermis on three sides. | |||
Others features:{{fact}} | |||
*Irregular [[acanthosis]]. | |||
*Longer rete ridges. | |||
DDx: | |||
*[[Venous lake]]. | |||
*Angiokeratoma-like changes in [[lichen sclerosus]].<ref name=pmid19187108>{{Cite journal | last1 = Luzar | first1 = B. | last2 = Neil | first2 = SM. | last3 = Calonje | first3 = E. | title = Angiokeratoma-like changes in extragenital and genital lichen sclerosus. | journal = J Cutan Pathol | volume = 36 | issue = 5 | pages = 540-2 | month = May | year = 2009 | doi = 10.1111/j.1600-0560.2008.01091.x | PMID = 19187108 }}</ref> | |||
===Images=== | |||
<gallery> | |||
Image:Angiokeratoma_-_low_mag.jpg | Angiokeratoma - low mag. (WC/Nephron) | |||
Image:Angiokeratoma_-_intermed_mag.jpg | Angiokeratoma - intermed. mag. (WC/Nephron) | |||
Image:Angiokeratoma_-_high_mag.jpg | Angiokeratoma - high mag. (WC/Nephron) | |||
</gallery> | |||
www: | |||
*[http://www.pathologyoutlines.com/images/skintumorangiokerat1.jpg Angiokeratoma (pathologyoutlines.com)]. | |||
==Sign out== | |||
<pre> | |||
SKIN LESION, LEFT POPITEAL FOSSA, PUNCH BIOPSY: | |||
- ANGIOKERATOMA. | |||
</pre> | |||
==See also== | |||
*[[Non-malignant skin disease]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Non-malignant skin disease]] | |||
[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||