Thyroid cytopathology: Difference between revisions

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===Colloid===
===Colloid===
Essentially - acellular crap with:
Paucicellular/acellular material with:<ref name=pmid15987502>{{cite journal |authors=Nguyen GK, Lee MW, Ginsberg J, Wragg T, Bilodeau D |title=Fine-needle aspiration of the thyroid: an overview |journal=Cytojournal |volume=2 |issue=1 |pages=12 |date=June 2005 |pmid=15987502 |pmc=1184092 |doi=10.1186/1742-6413-2-12 |url=}}</ref>
*Irregular/sharp borders.
*Irregular/sharp borders.
*Cracks - '''key feature'''.
*Cracks - '''key feature'''.
*Bubble pattern.
*Dark (uniform) staining with [[Romanowsky stain|Romanowsky type stains]].
*Dark (uniform) staining with [[Romanowsky stain|Romanowsky type stains]].
**Green edge + red/orange centre with [[Pap stain]].
**Green edge + red/orange centre with [[Pap stain]].
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*Granular chromatin.
*Granular chromatin.
*Cytoplasm - often not distinct.
*Cytoplasm - often not distinct.
*Scattered naked nuclei.<ref name=pmid24255635>{{Cite journal  | last1 = Heo | first1 = I. | last2 = Park | first2 = S. | last3 = Jung | first3 = CW. | last4 = Koh | first4 = JS. | last5 = Lee | first5 = SS. | last6 = Seol | first6 = H. | last7 = Choi | first7 = HS. | last8 = Cho | first8 = SY. | title = Fine needle aspiration cytology of parathyroid lesions. | journal = Korean J Pathol | volume = 47 | issue = 5 | pages = 466-71 | month = Oct | year = 2013 | doi = 10.4132/KoreanJPathol.2013.47.5.466 | PMID = 24255635 }}</ref>
*+/-Nuclear moulding.
*+/-Nuclear moulding.
*+/-Nuclear overlap.
*+/-Nuclear overlap.
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Images:
Images:
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770637/figure/f1/ Parathyroid gland (nih.gov)].<ref name=pmid15790694>{{Cite journal  | last1 = Johnson | first1 = SJ. | last2 = Sheffield | first2 = EA. | last3 = McNicol | first3 = AM. | title = Best practice no 183. Examination of parathyroid gland specimens. | journal = J Clin Pathol | volume = 58 | issue = 4 | pages = 338-42 | month = Apr | year = 2005 | doi = 10.1136/jcp.2002.002550 | PMID = 15790694 | PMC = 1770637 }}</ref>
*[http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770637/figure/f1/ Parathyroid gland (nih.gov)].<ref name=pmid15790694>{{Cite journal  | last1 = Johnson | first1 = SJ. | last2 = Sheffield | first2 = EA. | last3 = McNicol | first3 = AM. | title = Best practice no 183. Examination of parathyroid gland specimens. | journal = J Clin Pathol | volume = 58 | issue = 4 | pages = 338-42 | month = Apr | year = 2005 | doi = 10.1136/jcp.2002.002550 | PMID = 15790694 | PMC = 1770637 }}</ref>
DDx of naked nuclei:
*[[Granular cell tumour]].
*Parathyroid.<ref name=pmid19283690/>


=Adequacy criteria=
=Adequacy criteria=
*>=60 follicular cells. †
*>=60 follicular cells. †
**If abundant colloid is present less follicular cells are accepted.
*No atypical cells.
*No atypical cells.


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Note: A repeat aspiration should be considered if clinically warranted.  
Note: A repeat aspiration should be considered if clinically warranted.  
</pre>
====Abundant colloid====
<pre>
Left Thyroid, FNA: BENIGN, see comment.
Note:
The specimen has abundant colloid. The background consists of histiocytes in keeping with a cyst.  The number of follicular cells falls below the typically desired threshold; however, the case is sufficient on the basis of the abundant colloid, as per the 2023 Bethesda System for Reporting Thyroid Cytopathology. The clinical impression is noted.
</pre>
</pre>


=Standard sign-out language=
=Standard sign-out language=
There is a standard way of describing thyroid cytopathology results.
There is a standard way of describing thyroid cytopathology results.
===Bethesda (2023)===
*A new iteration of Bethesda 2009.


===Bethesda (2009)===
===Bethesda (2009)===
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