Difference between revisions of "Prostate cancer with neuroendocrine differentiation"
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''' | '''Prostate cancer with neuroendocrine differentiation''' is a rare group of [[prostate cancer]]s that is hypothesized to evolve in the context androgen deprivation therapy.<ref name=pmid24705311>{{Cite journal | last1 = Epstein | first1 = JI. | last2 = Amin | first2 = MB. | last3 = Beltran | first3 = H. | last4 = Lotan | first4 = TL. | last5 = Mosquera | first5 = JM. | last6 = Reuter | first6 = VE. | last7 = Robinson | first7 = BD. | last8 = Troncoso | first8 = P. | last9 = Rubin | first9 = MA. | title = Proposed morphologic classification of prostate cancer with neuroendocrine differentiation. | journal = Am J Surg Pathol | volume = 38 | issue = 6 | pages = 756-67 | month = Jun | year = 2014 | doi = 10.1097/PAS.0000000000000208 | PMID = 24705311 }}</ref> | ||
'''Neuroendocrine carcinoma of the prostate''' redirect here. | |||
==General== | |||
*Treatment: platinum based therapy. | |||
==Subclassification== | |||
It is subclassified as per Epstein ''et al.'':<ref name=pmid24705311/> | It is subclassified as per Epstein ''et al.'':<ref name=pmid24705311/> | ||
*Usual prostate adenocarcinoma with neuroendocrine differentiation. | *Usual prostate adenocarcinoma with neuroendocrine differentiation. | ||
| Line 10: | Line 16: | ||
==IHC== | ==IHC== | ||
*[[PSA]] typically negative in | *[[PSA]] typically negative in neuroendocrine carcinomas. | ||
==See also== | ==See also== | ||
*[[Prostate cancer]]. | *[[Prostate cancer]]. | ||
*[[Neuroendocrine carcinoma]]. | *[[Neuroendocrine carcinoma]]. | ||
*[[Paneth cell-like change of the prostate gland]]. | |||
==References== | ==References== | ||
Latest revision as of 22:47, 19 March 2018
Prostate cancer with neuroendocrine differentiation is a rare group of prostate cancers that is hypothesized to evolve in the context androgen deprivation therapy.[1]
Neuroendocrine carcinoma of the prostate redirect here.
General
- Treatment: platinum based therapy.
Subclassification
It is subclassified as per Epstein et al.:[1]
- Usual prostate adenocarcinoma with neuroendocrine differentiation.
- Adenocarcinoma with Paneth cell neuroendocrine differentiation.
- Carcinoid tumour of the prostate.
- Small cell carcinoma of the prostate gland.
- Large cell neuroendocrine carcinoma of the prostate.
- Mixed (small and/or large cell) neuroendocrine carcinoma-acinar adenocarcinoma.
IHC
- PSA typically negative in neuroendocrine carcinomas.
See also
References
- ↑ 1.0 1.1 Epstein, JI.; Amin, MB.; Beltran, H.; Lotan, TL.; Mosquera, JM.; Reuter, VE.; Robinson, BD.; Troncoso, P. et al. (Jun 2014). "Proposed morphologic classification of prostate cancer with neuroendocrine differentiation.". Am J Surg Pathol 38 (6): 756-67. doi:10.1097/PAS.0000000000000208. PMID 24705311.