Difference between revisions of "Syringoma"
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Syringoma -- low mag.jpg | |||
| Width = | |||
| Caption = Syringoma. [[H&E stain]]. (WC) | |||
| Synonyms = | |||
| Micro = bilayered cytologically bland ducts with tadpole-like appearance | |||
| Subtypes = | |||
| LMDDx = | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = usually lower eyelid lesion | |||
| Grossing = [[unoriented skin ellipse grossing]], [[oriented skin ellipse grossing]] | |||
| Staging = | |||
| Site = [[skin]], [[eyelid]] - see ''[[dermatologic neoplasms]]'' | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = classically female | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Syringoma''' is a benign skin lesion. | |||
==General== | |||
*Benign sweat duct tumour. | |||
*Eccrine differentiation. | |||
*Classically lower [[eyelid]].<ref>{{Ref PBoD8|1177}}</ref><ref name=pmid17326243/> | |||
*Typical female - female:male = 6.6:1.<ref name=pmid17326243>{{cite journal |authors=Lee JH, Chang JY, Lee KH |title=Syringoma: a clinicopathologic and immunohistologic study and results of treatment |journal=Yonsei Med J |volume=48 |issue=1 |pages=35–40 |date=February 2007 |pmid=17326243 |pmc=2628001 |doi=10.3349/ymj.2007.48.1.35 |url=}}</ref> | |||
==Microscopic== | |||
Features:<ref>URL: [http://emedicine.medscape.com/article/1059871-diagnosis http://emedicine.medscape.com/article/1059871-diagnosis]. Accessed on: 12 May 2010.</ref> | |||
*Proliferation of benign ducts with lined by a bilayer (as in normal sweat ducts) with abnormal architecture: | |||
**Tadpole like appearing ducts. | |||
DDx: | |||
*Syringomatous adenomas of nipple (AKA syringoma of the nipple).<ref name=pmid22355740>{{Cite journal | last1 = Boecker | first1 = W. | last2 = Junkers | first2 = T. | last3 = Reusch | first3 = M. | last4 = Buerger | first4 = H. | last5 = Korsching | first5 = E. | last6 = Metze | first6 = D. | last7 = Decker | first7 = T. | last8 = Loening | first8 = T. | last9 = Lange | first9 = A. | title = Origin and differentiation of breast nipple syringoma. | journal = Sci Rep | volume = 2 | issue = | pages = 226 | month = | year = 2012 | doi = 10.1038/srep00226 | PMID = 22355740 |URL = http://www.nature.com/srep/2012/120117/srep00226/full/srep00226.html }}</ref> | |||
*[[Chondroid syringoma]]. (???) | |||
===Images=== | |||
<gallery> | |||
Image: Syringoma -- very low mag.jpg | Syringoma - very low mag. | |||
Image: Syringoma -- low mag.jpg | Syringoma - low mag. | |||
Image: Syringoma -- intermed mag.jpg | Syringoma - intermed. mag. | |||
Image: Syringoma - alt -- intermed mag.jpg | Syringoma - intermed. mag. | |||
Image: Syringoma -- high mag.jpg | Syringoma - high mag. | |||
</gallery> | |||
<gallery> | |||
Image: SkinTumors-P8080545.JPG | Syringoma | |||
</gallery> | |||
*[http://www.flickr.com/photos/euthman/2329061316/ Syringoma (flickr.com)]. | |||
*[http://dermatology.cdlib.org/144/tumors/axillary_syringoma/2.jpg Syringoma (dermatology.cdlib.org)].<ref>{{Cite journal | last1 = Nosrati | first1 = N. | last2 = Coleman | first2 = NM. | last3 = Hsu | first3 = S. | title = Axillary syringomas. | journal = Dermatol Online J | volume = 14 | issue = 4 | pages = 13 | month = | year = 2008 | doi = | PMID = 18627735 |URL = http://dermatology.cdlib.org/144/tumors/axillary_syringoma/hsu.html}}</ref> | |||
==Sign out== | |||
<pre> | |||
A. Right Lower Eyelid Lesion, Biopsy: | |||
- Benign syringoma. | |||
</pre> | |||
==See also== | |||
*[[Dermatologic neoplasms]]. | |||
*[[Chondroid syringoma]]. | |||
==References== | |||
{{Reflist|2}} | |||
[[Category:Diagnosis]] | |||
[[Category:Dermatopathology]] | |||
Latest revision as of 04:10, 1 November 2024
| Syringoma | |
|---|---|
| Diagnosis in short | |
 Syringoma. H&E stain. (WC) | |
|
| |
| LM | bilayered cytologically bland ducts with tadpole-like appearance |
| Gross | usually lower eyelid lesion |
| Grossing notes | unoriented skin ellipse grossing, oriented skin ellipse grossing |
| Site | skin, eyelid - see dermatologic neoplasms |
|
| |
| Clinical history | classically female |
| Prognosis | benign |
Syringoma is a benign skin lesion.
General
- Benign sweat duct tumour.
- Eccrine differentiation.
- Classically lower eyelid.[1][2]
- Typical female - female:male = 6.6:1.[2]
Microscopic
Features:[3]
- Proliferation of benign ducts with lined by a bilayer (as in normal sweat ducts) with abnormal architecture:
- Tadpole like appearing ducts.
DDx:
- Syringomatous adenomas of nipple (AKA syringoma of the nipple).[4]
- Chondroid syringoma. (???)
Images
Syringoma - very low mag.
Syringoma - low mag.
Syringoma - intermed. mag.
Syringoma - intermed. mag.
Syringoma - high mag.
Syringoma
Sign out
A. Right Lower Eyelid Lesion, Biopsy: - Benign syringoma.
See also
References
- ↑ Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Aster, Jon (2009). Robbins and Cotran pathologic basis of disease (8th ed.). Elsevier Saunders. pp. 1177. ISBN 978-1416031215.
- ↑ 2.0 2.1 Lee JH, Chang JY, Lee KH (February 2007). "Syringoma: a clinicopathologic and immunohistologic study and results of treatment". Yonsei Med J 48 (1): 35–40. doi:10.3349/ymj.2007.48.1.35. PMC 2628001. PMID 17326243. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628001/.
- ↑ URL: http://emedicine.medscape.com/article/1059871-diagnosis. Accessed on: 12 May 2010.
- ↑ Boecker, W.; Junkers, T.; Reusch, M.; Buerger, H.; Korsching, E.; Metze, D.; Decker, T.; Loening, T. et al. (2012). "Origin and differentiation of breast nipple syringoma.". Sci Rep 2: 226. doi:10.1038/srep00226. PMID 22355740.
- ↑ Nosrati, N.; Coleman, NM.; Hsu, S. (2008). "Axillary syringomas.". Dermatol Online J 14 (4): 13. PMID 18627735.