Serous borderline tumour: Difference between revisions
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| Caption = Serous borderline tumour with a micropapillary pattern. [[H&E stain]]. | | Caption = Serous borderline tumour with a micropapillary pattern. [[H&E stain]]. | ||
| Synonyms = | | Synonyms = | ||
| Micro = | | Micro = cuboidal to columnar epithelium with mild to moderate atypia, no invasion (see below), "sparse" mitoses ,+/-[[psammoma bodies]], +/-micropapillary architecture (often described as a ''medusa head'' pattern) | ||
| Subtypes = | | Subtypes = serous borderline tumour (SBT) with micropapillary pattern, typical SBT ''or'' SBT not otherwise specified | ||
| LMDDx = [[serous cystadenoma]], [[serous carcinoma of the ovary]], [[clear cell carcinoma of the ovary]] | | LMDDx = [[serous cystadenoma of the ovary|serous cystadenoma]], [[serous carcinoma of the ovary]], [[clear cell carcinoma of the ovary]] | ||
| Stains = | | Stains = | ||
| IHC = | | IHC = | ||
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Features:<ref name=Ref_GP399>{{Ref GP|399}}</ref> | Features:<ref name=Ref_GP399>{{Ref GP|399}}</ref> | ||
*Cuboidal to columnar epithelium with mild to moderate atypia. | *Cuboidal to columnar epithelium with mild to moderate atypia. | ||
* | *Non-invasive. | ||
*"Sparse" mitoses. | *"Sparse" mitoses. | ||
*+/-[[Psammoma bodies]]. | *+/-[[Psammoma bodies]]. | ||
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**Invasive cells are "pink", i.e. have abundant eosinophilic cytoplasm,<ref name=Ref_GP399/>; also, cells usu. large (~2-3x size of non-invasive component), and typically have an enlarged nucleus (~2x non-invasive component). | **Invasive cells are "pink", i.e. have abundant eosinophilic cytoplasm,<ref name=Ref_GP399/>; also, cells usu. large (~2-3x size of non-invasive component), and typically have an enlarged nucleus (~2x non-invasive component). | ||
*[[Clear cell carcinoma of the ovary]] - classically associated with [[endometriosis]], have simpler, smaller papillae without branching. | *[[Clear cell carcinoma of the ovary]] - classically associated with [[endometriosis]], have simpler, smaller papillae without branching. | ||
*[[Serous cystadenoma]]. | *[[Serous cystadenoma of the ovary]]. | ||
===Images=== | ===Images=== | ||
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<pre> | <pre> | ||
Cyst and Right Fallopian Tube, Excision: | Cyst and Right Fallopian Tube, Excision: | ||
- SEROUS BORDERLINE TUMOUR with micropapillary architecture, see comment. | |||
- Fallopian tube within normal limits. | |||
- NEGATIVE for evidence of invasion. | |||
Comment: | Comment: | ||