Difference between revisions of "Glomangiopericytoma"
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==General== | ==General== | ||
*May be associated with ''oncogenic osteomalacia''.<ref name=pmid22430770/> | *May be associated with ''[[oncogenic osteomalacia]]''.<ref name=pmid22430770/> | ||
*Thought to arise from the pericytes.<ref name=pmid22801124>{{Cite journal | last1 = Arpaci | first1 = RB. | last2 = Kara | first2 = T. | last3 = Vayisoğlu | first3 = Y. | last4 = Ozgur | first4 = A. | last5 = Ozcan | first5 = C. | title = Sinonasal glomangiopericytoma. | journal = J Craniofac Surg | volume = 23 | issue = 4 | pages = 1194-6 | month = Jul | year = 2012 | doi = 10.1097/SCS.0b013e31824e6d09 | PMID = 22801124 }}</ref> | *Thought to arise from the pericytes.<ref name=pmid22801124>{{Cite journal | last1 = Arpaci | first1 = RB. | last2 = Kara | first2 = T. | last3 = Vayisoğlu | first3 = Y. | last4 = Ozgur | first4 = A. | last5 = Ozcan | first5 = C. | title = Sinonasal glomangiopericytoma. | journal = J Craniofac Surg | volume = 23 | issue = 4 | pages = 1194-6 | month = Jul | year = 2012 | doi = 10.1097/SCS.0b013e31824e6d09 | PMID = 22801124 }}</ref> | ||
*Rare <1% of sinonasal tumours.<ref name=pmid22801124/> | *Rare <1% of sinonasal tumours.<ref name=pmid22801124/> | ||
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*[[Phosphaturic mesenchymal tumour, mixed connective tissue type]] - grungy calcs, acellular matrix deposition. | *[[Phosphaturic mesenchymal tumour, mixed connective tissue type]] - grungy calcs, acellular matrix deposition. | ||
*Other [[small round cell tumours]]. | *Other [[small round cell tumours]]. | ||
*[[Biphenotypic sinonasal sarcoma]] - head and neck lesion. | |||
===Images=== | ===Images=== | ||
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[[Category:Diagnosis]] | [[Category:Diagnosis]] | ||
[[Category:Weird stuff]] | |||
Latest revision as of 16:26, 13 March 2016
Glomangiopericytoma, also known as sinonasal-type hemangiopericytoma and sinonasal hemangiopericytoma,
Sinonasal hemangiopericytoma may be abbreviated SNHPC.[1]
General
- May be associated with oncogenic osteomalacia.[1]
- Thought to arise from the pericytes.[2]
- Rare <1% of sinonasal tumours.[2]
Microscopic
Features:[1]
- Short spindle cells/epithelioid cells with:
- Bland round/oval nuclei with fine chromatin.
- Scant cytoplasm.
Note:
- Superficial submucosal tissue spared.
DDx:
- Phosphaturic mesenchymal tumour, mixed connective tissue type - grungy calcs, acellular matrix deposition.
- Other small round cell tumours.
- Biphenotypic sinonasal sarcoma - head and neck lesion.
Images
IHC
Features:[3]
- Vimentin +ve.
- SMA +ve.
- MSA +ve.
- CD31 -ve.
- CD34 -ve.
See also
References
- ↑ 1.0 1.1 1.2 1.3 1.4 Brandwein-Gensler, M.; Siegal, GP. (Mar 2012). "Striking pathology gold: a singular experience with daily reverberations: sinonasal hemangiopericytoma (glomangiopericytoma) and oncogenic osteomalacia.". Head Neck Pathol 6 (1): 64-74. doi:10.1007/s12105-012-0337-8. PMID 22430770.
- ↑ 2.0 2.1 Arpaci, RB.; Kara, T.; Vayisoğlu, Y.; Ozgur, A.; Ozcan, C. (Jul 2012). "Sinonasal glomangiopericytoma.". J Craniofac Surg 23 (4): 1194-6. doi:10.1097/SCS.0b013e31824e6d09. PMID 22801124.
- ↑ 3.0 3.1 Sun, Q.; Zhang, C.; Chen, W.; He, Y. (2013). "The molecular mechanisms on glomangiopericytoma invasion.". Orphanet J Rare Dis 8: 152. doi:10.1186/1750-1172-8-152. PMID 24074285.