Metaphyseal fibrous defect: Difference between revisions
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| EHVSC_mult = | | EHVSC_mult = | ||
| pathprotocols = | | pathprotocols = | ||
| wikipedia = | | wikipedia = Nonossifying fibroma | ||
| pathoutlines = {{Pathologyoutlines|topic/bonemetaphysealfibrousdefect}} | | pathoutlines = {{Pathologyoutlines|topic/bonemetaphysealfibrousdefect}} | ||
| rosaicollection = | | rosaicollection = | ||
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*Often small lesions discovered as an radiographic incidentaloma. | *Often small lesions discovered as an radiographic incidentaloma. | ||
*Rarely seen as a pathologic specimen (should not be biopsied). | *Rarely seen as a pathologic specimen (should not be biopsied). | ||
*May be seen in the context of ''Jaffe-Campanacci syndrome''.<ref>URL: [http://www.bonetumor.org/plasma-cell-tumors/jaffe-campanacci-syndrome http://www.bonetumor.org/plasma-cell-tumors/jaffe-campanacci-syndrome]. Accessed on: October 14, 2014.</ref> | *May be seen in the context of ''Jaffe-Campanacci syndrome'' which may be a presentation of Neurofibromatosis Type 1.<ref>URL: [http://www.bonetumor.org/plasma-cell-tumors/jaffe-campanacci-syndrome http://www.bonetumor.org/plasma-cell-tumors/jaffe-campanacci-syndrome]. Accessed on: October 14, 2014.</ref><ref>{{Cite journal | last1 = Stewart | first1 = DR. | last2 = Brems | first2 = H. | last3 = Gomes | first3 = AG. | last4 = Ruppert | first4 = SL. | last5 = Callens | first5 = T. | last6 = Williams | first6 = J. | last7 = Claes | first7 = K. | last8 = Bober | first8 = MB. | last9 = Hachen | first9 = R. | title = Jaffe-Campanacci syndrome, revisited: detailed clinical and molecular analyses determine whether patients have neurofibromatosis type 1, coincidental manifestations, or a distinct disorder. | journal = Genet Med | volume = 16 | issue = 6 | pages = 448-59 | month = Jun | year = 2014 | doi = 10.1038/gim.2013.163 | PMID = 24232412 }} | ||
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*Radiographic diagnosis. | *Radiographic diagnosis. | ||
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*Eccentric location. | *Eccentric location. | ||
===Radiology=== | |||
*Sharply demarcated, lucent, loculated, meta-diaphyseal lesion. | *Sharply demarcated, lucent, loculated, meta-diaphyseal lesion. | ||
*Surrounded by a rim of sclerotic bone. | *Surrounded by a rim of sclerotic bone. | ||
<gallery> | |||
Image:NOF 1.jpg|Nonossifying fibroma. (WC) | |||
</gallery> | |||
==Microscopic== | ==Microscopic== | ||