Inverted urothelial papilloma: Difference between revisions
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{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Inverted_papilloma_high_mag.jpg | |||
| Width = | |||
| Caption = Inverted urothelial papilloma. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = like papillomas... but grow downward; '''never''' have an exophytic component; nests have peripheral palisading of nuclei - '''important''' | |||
| Subtypes = | |||
| LMDDx = [[low grade papillary urothelial carcinoma]] with an inverted growth pattern | |||
| Stains = | |||
| IHC = Ki-67 -ve, CK20 -ve, p53 -ve (rarely +ve) | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[urothelium]] - usu. [[urinary bladder]] | |||
| Assdx = | |||
| Syndromes = | |||
| Clinicalhx = | |||
| Signs = | |||
| Symptoms = | |||
| Prevalence = uncommon | |||
| Bloodwork = | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = benign | |||
| Other = | |||
| ClinDDx = | |||
| Tx = | |||
}} | |||
'''Inverted urothelial papilloma''', also '''inverted papilloma''', is a benign [[urothelium|urothelial]] lesion that may be confused with [[urothelial carcinoma]]. | '''Inverted urothelial papilloma''', also '''inverted papilloma''', is a benign [[urothelium|urothelial]] lesion that may be confused with [[urothelial carcinoma]]. | ||
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DDx: | DDx: | ||
*[[Low grade papillary urothelial carcinoma]] with an inverted growth pattern. | *[[Low grade papillary urothelial carcinoma]] with an inverted growth pattern. | ||
*[[Cystitis cystica]]. | |||
===Images=== | ===Images=== | ||
====Case 1==== | |||
<gallery> | <gallery> | ||
Image:Inverted_papilloma_high_mag.jpg | Inverted papilloma - high mag. (WC/Nephron) | Image:Inverted_papilloma_high_mag.jpg | Inverted papilloma - high mag. (WC/Nephron) | ||
Image:Inverted_papilloma_intermed_mag.jpg | Inverted papilloma - intermed. mag. (WC/Nephron) | Image:Inverted_papilloma_intermed_mag.jpg | Inverted papilloma - intermed. mag. (WC/Nephron) | ||
</gallery> | |||
====Case 2==== | |||
<gallery> | |||
Image: Bladder inverted papilloma histopathology (1).jpg | IUP. (WC/KGH) | |||
Image: Bladder inverted papilloma histopathology (2).jpg | IUP. (WC/KGH) | |||
Image: Bladder inverted papilloma histopathology (3).jpg | IUP. (WC/KGH) | |||
</gallery> | </gallery> | ||
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==See also== | ==See also== | ||
*[[Urothelium]]. | *[[Urothelium]]. | ||
*[[Urothelial papilloma]]. | |||
*[[Cystitis cystica]]. | *[[Cystitis cystica]]. | ||
==Sign out== | |||
<pre> | |||
Bladder Tumour, Transurthral Resection: | |||
- Inverted papilloma. | |||
</pre> | |||
===Micro=== | |||
The sections show urothelial mucosa with densely packed urothelial nests with peripheral palisading. The cells of the urothelial nests are bland. Proliferative activity is not apparent. Definite papillae are absent. No exophytic component is apparent. | |||
==References== | ==References== | ||