Difference between revisions of "Pseudopyloric mucous glands"
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[[Image:Pseudopyloric mucous glands - 3 -- very high mag.jpg|thumb|right|[[Micrograph]] showing pseudopyloric mucous glands. [[H&E stain]].]] | [[Image:Pseudopyloric mucous glands - 3 -- very high mag.jpg|thumb|right|[[Micrograph]] showing pseudopyloric mucous glands (bottom) and intestinal epithelium (top). [[H&E stain]].]] | ||
'''Pseudopyloric mucous glands''', also '''pyloric gland metaplasia''',<ref name=medunigraz>URL: [http://www.medunigraz.at/22698 http://www.medunigraz.at/22698]. Accessed on: 6 August 2013.</ref> is a change seen intestine. It is associated with [[Crohn's disease]]. | '''Pseudopyloric mucous glands''', also '''pyloric gland metaplasia''',<ref name=medunigraz>URL: [http://www.medunigraz.at/22698 http://www.medunigraz.at/22698]. Accessed on: 6 August 2013.</ref> is a change seen the intestine. It is associated with [[Crohn's disease]]. | ||
Pseudopyloric mucous glands is abbreviated '''PMG'''. Pyloric gland metaplasia is abbreviated '''PGM'''. | Pseudopyloric mucous glands is abbreviated '''PMG'''. Pyloric gland metaplasia is abbreviated '''PGM'''. | ||
==General== | ==General== | ||
* | *May be seen in [[Crohn's disease]] in the [[terminal ileum]].<ref>{{Cite journal | last1 = Geboes | first1 = K. | last2 = Ectors | first2 = N. | last3 = D'Haens | first3 = G. | last4 = Rutgeerts | first4 = P. | title = Is ileoscopy with biopsy worthwhile in patients presenting with symptoms of inflammatory bowel disease? | journal = Am J Gastroenterol | volume = 93 | issue = 2 | pages = 201-6 | month = Feb | year = 1998 | doi = 10.1111/j.1572-0241.1998.00201.x | PMID = 9468242 }}</ref> | ||
*Suggestive of [[Crohn's disease]] in [[pouchitis]] but ''not'' diagnostic.<ref name=pmid23543088>{{Cite journal | last1 = Agarwal | first1 = S. | last2 = Stucchi | first2 = AF. | last3 = Dendrinos | first3 = K. | last4 = Cerda | first4 = S. | last5 = O'Brien | first5 = MJ. | last6 = Becker | first6 = JM. | last7 = Heeren | first7 = T. | last8 = Farraye | first8 = FA. | title = Is pyloric gland metaplasia in ileal pouch biopsies a marker for Crohn's disease? | journal = Dig Dis Sci | volume = 58 | issue = 10 | pages = 2918-25 | month = Oct | year = 2013 | doi = 10.1007/s10620-013-2655-4 | PMID = 23543088 }}</ref> | |||
==Microscopic== | ==Microscopic== | ||
Features: | Features:<ref name=pmid23925821>{{Cite journal | last1 = Weber | first1 = CR. | last2 = Rubin | first2 = DT. | title = Chronic pouchitis versus recurrent Crohn's disease: a diagnostic challenge. | journal = Dig Dis Sci | volume = 58 | issue = 10 | pages = 2748-50 | month = Oct | year = 2013 | doi = 10.1007/s10620-013-2816-5 | PMID = 23925821 }}</ref> | ||
*Round glands with | *Round glands composed of tall columnar cells with: | ||
**Abundant pale (pink) cytoplasm. | |||
**Small basal nuclei. | |||
*Usually in the deep aspect of the mucosa. | *Usually in the deep aspect of the mucosa. | ||
Note: | |||
*The lining cells look somewhat like stubby champagne flutes. | |||
===Images=== | ===Images=== | ||
<gallery> | <gallery> | ||
Image: Pseudopyloric mucous glands -- low mag.jpg | PMG - | Image: Pseudopyloric mucous glands -- low mag.jpg | PMG - low mag. | ||
Image: Pseudopyloric mucous glands -- intermed mag.jpg | PMG - intermed. mag. | Image: Pseudopyloric mucous glands -- intermed mag.jpg | PMG - intermed. mag. | ||
Image: Pseudopyloric mucous glands -- high mag.jpg | PMG - high mag. | Image: Pseudopyloric mucous glands -- high mag.jpg | PMG - high mag. | ||
| Line 24: | Line 30: | ||
Image: Pseudopyloric mucous glands - 3b -- high mag.jpg | PMG - high mag. | Image: Pseudopyloric mucous glands - 3b -- high mag.jpg | PMG - high mag. | ||
Image: Pseudopyloric mucous glands - 3 -- very high mag.jpg | PMG - very high mag. | Image: Pseudopyloric mucous glands - 3 -- very high mag.jpg | PMG - very high mag. | ||
</gallery> | |||
<gallery> | |||
Image:Champagne flute and bottle.jpg | Champagne flute. (WC) | |||
</gallery> | </gallery> | ||
Latest revision as of 20:13, 21 May 2014
Pseudopyloric mucous glands, also pyloric gland metaplasia,[1] is a change seen the intestine. It is associated with Crohn's disease.
Pseudopyloric mucous glands is abbreviated PMG. Pyloric gland metaplasia is abbreviated PGM.
General
- May be seen in Crohn's disease in the terminal ileum.[2]
- Suggestive of Crohn's disease in pouchitis but not diagnostic.[3]
Microscopic
Features:[4]
- Round glands composed of tall columnar cells with:
- Abundant pale (pink) cytoplasm.
- Small basal nuclei.
- Usually in the deep aspect of the mucosa.
Note:
- The lining cells look somewhat like stubby champagne flutes.
Images
PMG - low mag.
PMG - intermed. mag.
PMG - high mag.
PMG - high mag.
PMG - very high mag.
PMG - high mag.
PMG - high mag.
PMG - very high mag.
Champagne flute. (WC)
See also
References
- ↑ URL: http://www.medunigraz.at/22698. Accessed on: 6 August 2013.
- ↑ Geboes, K.; Ectors, N.; D'Haens, G.; Rutgeerts, P. (Feb 1998). "Is ileoscopy with biopsy worthwhile in patients presenting with symptoms of inflammatory bowel disease?". Am J Gastroenterol 93 (2): 201-6. doi:10.1111/j.1572-0241.1998.00201.x. PMID 9468242.
- ↑ Agarwal, S.; Stucchi, AF.; Dendrinos, K.; Cerda, S.; O'Brien, MJ.; Becker, JM.; Heeren, T.; Farraye, FA. (Oct 2013). "Is pyloric gland metaplasia in ileal pouch biopsies a marker for Crohn's disease?". Dig Dis Sci 58 (10): 2918-25. doi:10.1007/s10620-013-2655-4. PMID 23543088.
- ↑ Weber, CR.; Rubin, DT. (Oct 2013). "Chronic pouchitis versus recurrent Crohn's disease: a diagnostic challenge.". Dig Dis Sci 58 (10): 2748-50. doi:10.1007/s10620-013-2816-5. PMID 23925821.