Alveolar soft part sarcoma: Difference between revisions
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| Caption = ASPS. [[H&E stain]]. | | Caption = ASPS. [[H&E stain]]. | ||
| Micro = large cells (~30-50 μm) with abundant eosinophilic cytoplasm and an eccentric nucleus +/-nucleolus, arranged in | | Micro = large cells (~30-50 μm) with abundant eosinophilic cytoplasm and an eccentric nucleus +/-nucleolus, arranged in nests/separated by thin septa - vaguely resembles alveoli (at low power) | ||
| Subtypes = | | Subtypes = | ||
| LMDDx = [[paraganglioma]], [[clear cell renal cell carcinoma]], [[alveolar rhabdomyosarcoma]] | | LMDDx = [[paraganglioma]], [[clear cell renal cell carcinoma]], [[alveolar rhabdomyosarcoma]] | ||
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| ClinDDx = | | ClinDDx = | ||
}} | }} | ||
'''Alveolar soft part sarcoma''', abbreviated '''ASPS''', is a rare malignant soft tissue lesion typically seen in younger individuals. | '''Alveolar soft part sarcoma''', abbreviated '''ASPS''', is a rare [[malignant]] soft tissue lesion typically seen in younger individuals. | ||
==General== | ==General== | ||
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==Microscopic== | ==Microscopic== | ||
Features:<ref name=Ref_WMSP627>{{Ref WMSP|627}}</ref> | Features:<ref name=Ref_WMSP627>{{Ref WMSP|627}}</ref> | ||
*Arranged in | *Arranged in nests/separated by thin septa; vaguely resembles alveoli (at low power). | ||
*Large cells (~30-50 μm) with abundant eosinophilic cytoplasm. | *Large cells (~30-50 μm) with abundant eosinophilic cytoplasm. | ||
**May be focally cleared. | **May be focally cleared. | ||