Difference between revisions of "Systemic lupus erythematosus lymphadenopathy"
Jump to navigation
Jump to search
| (6 intermediate revisions by the same user not shown) | |||
| Line 1: | Line 1: | ||
{{ Infobox diagnosis | |||
| Name = {{PAGENAME}} | |||
| Image = Systemic_lupus_erythematosus_lymphadenopathy_-_very_high_mag.jpg | |||
| Width = | |||
| Caption = Systemic lupus erythematosus lymphadenopathy. [[H&E stain]]. | |||
| Synonyms = | |||
| Micro = lymph node with [[necrosis]], hematoxylin bodies (in necrotic foci) | |||
| Subtypes = | |||
| LMDDx = [[Kikuchi disease]] | |||
| Stains = | |||
| IHC = | |||
| EM = | |||
| Molecular = | |||
| IF = | |||
| Gross = | |||
| Grossing = | |||
| Site = [[lymph node]] - see ''[[lymph node pathology]]'' | |||
| Assdx = [[systemic lupus erythematosus]] | |||
| Syndromes = | |||
| Clinicalhx = +/-hx of [[systemic lupus erythematosus]] | |||
| Signs = see ''[[systemic lupus erythematosus]]'' | |||
| Symptoms = see ''[[systemic lupus erythematosus]]'' | |||
| Prevalence = uncommon | |||
| Bloodwork = see ''[[systemic lupus erythematosus]]'' | |||
| Rads = | |||
| Endoscopy = | |||
| Prognosis = | |||
| Other = | |||
| ClinDDx = [[lymphoma]], other causes of lymphadenopathy | |||
| Tx = treatment for [[SLE]] | |||
}} | |||
'''Systemic lupus erythematosus lymphadenopathy''' is a very rare [[lymph node pathology]] seen in [[systemic lupus erythematosus]]. | '''Systemic lupus erythematosus lymphadenopathy''' is a very rare [[lymph node pathology]] seen in [[systemic lupus erythematosus]]. | ||
==General== | ==General== | ||
*Lymphadenopathy associated with [[systemic lupus erythematosus]] (SLE). | *Lymphadenopathy associated with [[systemic lupus erythematosus]] (SLE). | ||
*Lymphadenopathy may be the first presentation of SLE.<ref name=pmid24048114>{{Cite journal | last1 = Smith | first1 = LW. | last2 = Petri | first2 = M. | title = Diffuse lymphadenopathy as the presenting manifestation of systemic lupus erythematosus. | journal = J Clin Rheumatol | volume = 19 | issue = 7 | pages = 397-9 | month = Oct | year = 2013 | doi = 10.1097/RHU.0b013e3182a6a924 | PMID = 24048114 }}</ref> | |||
Clinical DDx: | |||
*[[Lymphoma]]. | |||
==Microscopic== | ==Microscopic== | ||
| Line 15: | Line 50: | ||
====Images==== | ====Images==== | ||
<gallery> | <gallery> | ||
Image:Systemic_lupus_erythematosus_lymphadenopathy_-_intermed_mag.jpg | SLE lymphadenopathy - intermed. mag. (WC) | |||
Image:Systemic_lupus_erythematosus_lymphadenopathy_-_high_mag.jpg | SLE lymphadenopathy - high mag. (WC) | Image:Systemic_lupus_erythematosus_lymphadenopathy_-_high_mag.jpg | SLE lymphadenopathy - high mag. (WC) | ||
Image:Systemic_lupus_erythematosus_lymphadenopathy_-_very_high_mag.jpg | SLE lymphadenopathy - very high mag. (WC) | Image:Systemic_lupus_erythematosus_lymphadenopathy_-_very_high_mag.jpg | SLE lymphadenopathy - very high mag. (WC) | ||
| Line 21: | Line 57: | ||
==See also== | ==See also== | ||
*[[Lymph node pathology]]. | *[[Lymph node pathology]]. | ||
*[[Systemic lupus erythematosus]]. | |||
==References== | ==References== | ||
Latest revision as of 05:44, 6 November 2014
| Systemic lupus erythematosus lymphadenopathy | |
|---|---|
| Diagnosis in short | |
 Systemic lupus erythematosus lymphadenopathy. H&E stain. | |
|
| |
| LM | lymph node with necrosis, hematoxylin bodies (in necrotic foci) |
| LM DDx | Kikuchi disease |
| Site | lymph node - see lymph node pathology |
|
| |
| Associated Dx | systemic lupus erythematosus |
| Clinical history | +/-hx of systemic lupus erythematosus |
| Signs | see systemic lupus erythematosus |
| Symptoms | see systemic lupus erythematosus |
| Prevalence | uncommon |
| Blood work | see systemic lupus erythematosus |
| Clin. DDx | lymphoma, other causes of lymphadenopathy |
| Treatment | treatment for SLE |
Systemic lupus erythematosus lymphadenopathy is a very rare lymph node pathology seen in systemic lupus erythematosus.
General
- Lymphadenopathy associated with systemic lupus erythematosus (SLE).
- Lymphadenopathy may be the first presentation of SLE.[1]
Clinical DDx:
Microscopic
Features:[2]
- Necrosis.
- Hematoxylin bodies (in necrotic foci).
- Dark blue irregular bodies on H&E.
DDx:
Images
SLE lymphadenopathy - intermed. mag. (WC)
SLE lymphadenopathy - high mag. (WC)
SLE lymphadenopathy - very high mag. (WC)
See also
References
- ↑ Smith, LW.; Petri, M. (Oct 2013). "Diffuse lymphadenopathy as the presenting manifestation of systemic lupus erythematosus.". J Clin Rheumatol 19 (7): 397-9. doi:10.1097/RHU.0b013e3182a6a924. PMID 24048114.
- ↑ Kojima, M.; Nakamura, S.; Itoh, H.; Yoshida, K.; Asano, S.; Yamane, N.; Komatsumoto, S.; Ban, S. et al. (1997). "Systemic lupus erythematosus (SLE) lymphadenopathy presenting with histopathologic features of Castleman' disease: a clinicopathologic study of five cases.". Pathol Res Pract 193 (8): 565-71. PMID 9406250.