Difference between revisions of "AE1/AE3"

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'''AE1/AE3''' is a common [[immunostain]] that marks keratins. It is considered a '''pankeratin''' by most.
{{ Infobox immunostain
| Name      = {{PAGENAME}}
| Image      = Small cell lung carcinoma, cytokeratin (AE1 AE3) immunostain (4388394288).jpg
| Width      =
| Caption    = AE1/AE3 staining in a [[small cell carcinoma]]. (WC/Yale Rosen)
| Abbrev    =
| Synonyms  =
| Similar    = [[Z622]]
| Clones    =     
| Use        = [[unknown primary]], confirm carcinoma
| Subspecial = 
| Pattern    = membranous
| Positive  = most carcinomas
| Negative  = most lymphomas, most sarcomas
| Other      =
}}
'''AE1/AE3''' is a common [[immunostain]] that marks keratins. It is considered a [[pankeratin]] by most.


==Positive==
==Positive==
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*[[Chordoma]].
*[[Chordoma]].
*[[Desmoplastic small round cell tumour]].
*[[Desmoplastic small round cell tumour]].
*Most [[epithelioid sarcomas]].
*Others.
*Others.


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*[[CK20]].
*[[CK20]].
*[[EMA]].
*[[EMA]].
*[[Cytokeratin Z622]].


[[Category:Immunohistochemistry]]
[[Category:Immunohistochemistry]]

Latest revision as of 20:53, 4 January 2019

AE1/AE3
Immunostain in short

AE1/AE3 staining in a small cell carcinoma. (WC/Yale Rosen)
Similar stains Z622
Use unknown primary, confirm carcinoma
Normal staining pattern membranous
Positive most carcinomas
Negative most lymphomas, most sarcomas

AE1/AE3 is a common immunostain that marks keratins. It is considered a pankeratin by most.

Positive

Sarcomas:

Negative

See also