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Difference between revisions of "Vermiform appendix"
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→Mucinous tumour
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**concurrent ''bilateral'' ovarian tumours suggests the tumour originated from the appendix and spread to the ovaries. | **concurrent ''bilateral'' ovarian tumours suggests the tumour originated from the appendix and spread to the ovaries. | ||
Classification<ref name=pmid12883241>{{cite journal |author=Misdraji J, Yantiss RK, Graeme-Cook FM, Balis UJ, Young RH |title=Appendiceal mucinous neoplasms: a clinicopathologic analysis of 107 cases |journal=Am. J. Surg. Pathol. |volume=27 |issue=8 |pages=1089–103 |year=2003 |month=August |pmid=12883241 |doi= |url=http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0147-5185&volume=27&issue=8&spage=1089}}</ref> | Classification:<ref name=pmid12883241>{{cite journal |author=Misdraji J, Yantiss RK, Graeme-Cook FM, Balis UJ, Young RH |title=Appendiceal mucinous neoplasms: a clinicopathologic analysis of 107 cases |journal=Am. J. Surg. Pathol. |volume=27 |issue=8 |pages=1089–103 |year=2003 |month=August |pmid=12883241 |doi= |url=http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0147-5185&volume=27&issue=8&spage=1089}}</ref> | ||
* | *Benign - ''low grade mucinous tumour''. | ||
* | *Borderline - ''mucinous tumour of uncertain malignant potential'' or ''borderline mucinous tumour''. | ||
* | *Balignant - ''mucinous adenocarcinoma''. | ||
Five year survival<ref name=pmid12883241/> | Five year survival (in a series of 107 cases):<ref name=pmid12883241/> | ||
{| class="wikitable" | {| class="wikitable" | ||
| ||'''5 year survival''' | | ||'''5 year survival''' | ||
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===Benign mucinous tumour=== | ===Benign mucinous tumour=== | ||
Microscopic: | |||
*Epithelium forms ''tufts'' - vaguely resemble ''serrations'', i.e. the ''saw-tooth'' pattern in hyperplastic polyps. | *Epithelium forms ''tufts'' - vaguely resemble ''serrations'', i.e. the ''saw-tooth'' pattern in hyperplastic polyps. | ||
*Single layer of epithelium. | *Single layer of epithelium. | ||
*Mucin contained (inside appendix only). | *Mucin contained (inside appendix only). | ||
Negatives | Negatives: | ||
*No marked nuclear atypia. | *No marked nuclear atypia. | ||
*No invasion into the lamina propria. | *No invasion into the lamina propria. | ||
===Borderline mucinous tumour=== | ===Borderline mucinous tumour=== | ||
Microscopic: | |||
*Same as benign, but mucin outside of the appendix. | *Same as benign, but mucin outside of the appendix. | ||
*Cells in mucin, i.e. cellular mucin. | *Cells in mucin, i.e. cellular mucin. | ||
===Malignant mucinous tumour=== | ===Malignant mucinous tumour=== | ||
Microscopic: | |||
*Marked nuclear pleomorphism. | *Marked nuclear pleomorphism. | ||
*Invasion into the wall. | *Invasion into the wall. | ||