48,833
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(→IHC: more) |
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DDx: | DDx: | ||
*May appear similar to oncotyoma -- particularily the eosinophilic variant. | *May appear similar to oncotyoma -- particularily the eosinophilic variant. | ||
**IHC | **A comparison based on histomorphology: ''[[Kidney_tumours#Tabular_comparison_of_oncocytoma_and_chromophobe_RCC|Tabular comparison between ChRCC & oncocytoma]]''. | ||
***No perinuclear clearing in oncocytoma. | |||
**IHC may be useful to differentiate (CK7: oncocytoma = cytoplasm +ve, chromophobe = cell membrane +ve). | |||
*Classic ChRCC may be challenging to differentiate from clear cell RCC. | *Classic ChRCC may be challenging to differentiate from clear cell RCC. | ||
**Perinuclear clearing is ''not'' seen in clear cell RCC. | **Perinuclear clearing is ''not'' seen in clear cell RCC. |
edits