Difference between revisions of "Cervical polyps"

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m (update)
(+other types of polyps)
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*Cause bleeding - due to trauma (???).
*Cause bleeding - due to trauma (???).


===Micro===
===Microscopic===
Features:
*May have mixed epithelium, i.e. squamous and endocervical type (with eosinophilic mucin).
*May have mixed epithelium, i.e. squamous and endocervical type (with eosinophilic mucin).
**Endocervical epithelium should have nuclei like that in the colon, i.e. small, round & basal.
**Endocervical epithelium should have nuclei like that in the colon, i.e. small, round & basal.
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*No mitoses.
*No mitoses.
*No nuclear atypia.
*No nuclear atypia.
*No stromal proliferation.


Notes:  
Notes:  
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Ref.:<ref>[http://pathologyoutlines.com/cervix.html#endocervpolyp http://pathologyoutlines.com/cervix.html#endocervpolyp]</ref>
Ref.:<ref>[http://pathologyoutlines.com/cervix.html#endocervpolyp http://pathologyoutlines.com/cervix.html#endocervpolyp]</ref>


==Fibroepithelial stromal polyp==
===General===
*Usually easy to recognize.<ref name=pmid10680891/>
===Microscopic===
Features:<ref name=pmid10680891/>
*Bland nuclei.
*Hypocellular.
==Pseudosarcomatous fibroepithelial stromal polyp==
===General===
*Uncommon.
*Wide age range.
*May be misdiagnosed as a sarcoma and overtreated.<ref name=pmid10680891>{{Cite journal  | last1 = Nucci | first1 = MR. | last2 = Young | first2 = RH. | last3 = Fletcher | first3 = CD. | title = Cellular pseudosarcomatous fibroepithelial stromal polyps of the lower female genital tract: an underrecognized lesion often misdiagnosed as sarcoma. | journal = Am J Surg Pathol | volume = 24 | issue = 2 | pages = 231-40 | month = Feb | year = 2000 | doi =  | PMID = 10680891 }}</ref>
*Similar lesions in [[vagina]] and [[vulva]].
===Microscopic===
Features:<ref name=pmid10680891/>
*Hypercellularity.
*Marked nuclear pleomorphism (common).
*+/-High mitotic rate ( > 10 mitoses / 10 [[HPF]]).
*+/-Atypical mitoses.
*No identifiable margin between lesion and normal - important feature.
*Scattered multinucleated stromal cells - usu. close to epithelium.
===IHC===
*Desmin +ve (common).
*SMA usu. -ve.
==See also==
==See also==
*[[Endometrial polyp]].
*[[Endometrial polyp]].

Revision as of 15:48, 8 August 2011

Cervical polyps are common entities that can be bothersome and are thus removed.

Endocervical polyps

Clinical

  • Usually 30-50 years old.
  • Cause bleeding - due to trauma (???).

Microscopic

Features:

  • May have mixed epithelium, i.e. squamous and endocervical type (with eosinophilic mucin).
    • Endocervical epithelium should have nuclei like that in the colon, i.e. small, round & basal.
  • Polypoid shape.
  • +/-Inflammation.
  • +/-Squamous metaplasia.

Negatives:

  • No mitoses.
  • No nuclear atypia.
  • No stromal proliferation.

Notes:

  • No histologic features separate cervical polyps from benign endocervical mucosa; ergo, they are often signed-out as "... consistent with cervical polyp."

Ref.:[1]

Fibroepithelial stromal polyp

General

  • Usually easy to recognize.[2]

Microscopic

Features:[2]

  • Bland nuclei.
  • Hypocellular.

Pseudosarcomatous fibroepithelial stromal polyp

General

  • Uncommon.
  • Wide age range.
  • May be misdiagnosed as a sarcoma and overtreated.[2]
  • Similar lesions in vagina and vulva.

Microscopic

Features:[2]

  • Hypercellularity.
  • Marked nuclear pleomorphism (common).
  • +/-High mitotic rate ( > 10 mitoses / 10 HPF).
  • +/-Atypical mitoses.
  • No identifiable margin between lesion and normal - important feature.
  • Scattered multinucleated stromal cells - usu. close to epithelium.

IHC

  • Desmin +ve (common).
  • SMA usu. -ve.

See also

References

  1. http://pathologyoutlines.com/cervix.html#endocervpolyp
  2. 2.0 2.1 2.2 2.3 Nucci, MR.; Young, RH.; Fletcher, CD. (Feb 2000). "Cellular pseudosarcomatous fibroepithelial stromal polyps of the lower female genital tract: an underrecognized lesion often misdiagnosed as sarcoma.". Am J Surg Pathol 24 (2): 231-40. PMID 10680891.