Talk:Breast pathology

Case with everything

Microscopic

1. The sections show breast tissue with a partially fibrous breast stroma, and glands with columnar cells, apocrine snouts and moderate, focal nuclear atypia in which nucleoli are easy to identify at the intermediate power objective. The glandular cells layer up to three cells thick. There are also glands with a columnar cell morphology and apocrine snouts, and dilated glands with flat and benign appearing epithelium. There is a focus of breast glands with a columnar cell morphology and apocrine snouts, with pale periglandular stroma. Focal microcalcifications, approximately 50-80 micrometers in size, are seen in benign breast glands.

1. The section small blood vessel-like channels in a dense, abundant interlobular stromal tissue. There are also glands with a columnar cell morphology and apocrine snouts, and dilated glands with flat and benign appearing epithelium.

Final diagnosis

1. Left breast, lumpectomy:
   • Flat epithelial atypia.
   • Columnar cell change.
   • Fibrocytic change.
   • Focal fibroadenomatoid change.
   • Microcalcifications in benign breast glands.
2. Left breast, lumpectomy:
   • Pseudoangiomatous stromal hyperplasia.
   • Columnar cell change.
   • Fibrocystic change.