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Difference between revisions of "Chromosomal translocations"
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===EWS associated=== | ====EWS associated==== | ||
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto" | {| class="wikitable sortable" style="margin-left:auto;margin-right:auto" | ||
| '''Tumour''' | | '''Tumour''' | ||
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|- | |- | ||
|} | |} | ||
===Lymphoma=== | |||
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto" | |||
| '''Tumour''' | |||
| '''Translocation(s)''' | |||
| '''Genes''' | |||
| '''Reference(s)''' | |||
|- | |||
| Follicular lymphoma | |||
| IGH-BCL2 | |||
| t(14,18) | |||
| <ref name=pmid18684042>{{Cite journal | last1 = Gu | first1 = K. | last2 = Chan | first2 = WC. | last3 = Hawley | first3 = RC. | title = Practical detection of t(14;18)(IgH/BCL2) in follicular lymphoma. | journal = Arch Pathol Lab Med | volume = 132 | issue = 8 | pages = 1355-61 | month = Aug | year = 2008 | doi = 10.1043/1543-2165(2008)132[1355:PDOBIF]2.0.CO;2 | PMID = 18684042 }}</ref> | |||
|- | |||
| Mantle cell lymphoma | |||
| genes ??? | |||
| t(11;14) | |||
| reference ??? | |||
|- | |||
| Burkitt lymphoma | |||
| genes ??? | |||
| t(8;14) | |||
| reference ??? | |||
|- | |||
<!-- | Tumour | |||
| Genes | |||
| Translocation | |||
| Reference --> | |||
|} | |||
===Leukemia=== | |||
{| class="wikitable sortable" style="margin-left:auto;margin-right:auto" | |||
| '''Tumour''' | |||
| '''Translocation(s)''' | |||
| '''Genes''' | |||
| '''Reference(s)''' | |||
|- | |||
| Chronic myelogenous leukemia | |||
| BCR-ABL | |||
| t(9;22) | |||
| <ref>{{Cite journal | last1 = Cilloni | first1 = D. | last2 = Saglio | first2 = G. | title = CML: a model for targeted therapy. | journal = Best Pract Res Clin Haematol | volume = 22 | issue = 3 | pages = 285-94 | month = Sep | year = 2009 | doi = 10.1016/j.beha.2009.04.004 | PMID = 19959080 }}</ref> | |||
|- | |||
| Acute promyelocytic leukemia (APL) | |||
| PML-RARA | |||
| t(15;17) | |||
| <ref name=pmid20306254>{{Cite journal | last1 = Grimwade | first1 = D. | last2 = Mistry | first2 = AR. | last3 = Solomon | first3 = E. | last4 = Guidez | first4 = F. | title = Acute promyelocytic leukemia: a paradigm for differentiation therapy. | journal = Cancer Treat Res | volume = 145 | issue = | pages = 219-35 | month = | year = 2010 | doi = 10.1007/978-0-387-69259-3_13 | PMID = 20306254 }}</ref> | |||
|- | |||
<!-- | tumour | |||
| genes (???) | |||
| translocation | |||
| reference (???) --> | |||
|} | |||
===Paediatric table=== | ===Paediatric table=== | ||
| Line 148: | Line 200: | ||
| Tumour | | Tumour | ||
| Reference --> | | Reference --> | ||
|} | |} | ||