Clear cell papillary renal cell tumour: Difference between revisions

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| Caption    = Clear cell papillary renal cell tumour. [[H&E stain]].
| Caption    = Clear cell papillary renal cell tumour. [[H&E stain]].
| Synonyms  = previously known as ''clear cell tubulopapillary renal cell carcinoma'' and ''clear cell papillary renal cell carcinoma''
| Synonyms  = previously known as ''clear cell tubulopapillary renal cell carcinoma'' and ''clear cell papillary renal cell carcinoma''
| Micro      = low ([[ISUP nucleolar grade|ISUP nucleolar]]) grade apical nuclei, clear cells, pseudopapillae, cystic and/or tubular architectures
| Micro      = low ([[ISUP nucleolar grade|ISUP nucleolar]]) grade apical nuclei (reverse polarized), clear cells, pseudopapillae, cystic and/or tubular architectures
| Subtypes  =
| Subtypes  =
| LMDDx      = [[clear cell renal cell carcinoma]], [[papillary renal cell carcinoma]], [[Xp11.2 translocation carcinoma]]
| LMDDx      = [[clear cell renal cell carcinoma]], [[papillary renal cell carcinoma]], [[Xp11.2 translocation carcinoma]]
| Stains    =
| Stains    =
| IHC        = CK7 +ve, AMACR -ve, CD10 -ve, TFE3 -ve
| IHC        = CK7 +ve, GATA-3 +ve, MA903 +ve, CD10 -ve, AMACR -ve, TFE3 -ve
| EM        =
| EM        =
| Molecular  =
| Molecular  =
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It was previously known as '''clear cell papillary renal cell carcinoma''', abbreviated '''CCPRCC'''
It was previously known as '''clear cell papillary renal cell carcinoma''', abbreviated '''CCPRCC'''


It is also previously known as '''clear cell tubulopapillary renal cell carcinoma''',<ref name=pmid21602815>{{Cite journal  | last1 = Rohan | first1 = SM. | last2 = Xiao | first2 = Y. | last3 = Liang | first3 = Y. | last4 = Dudas | first4 = ME. | last5 = Al-Ahmadie | first5 = HA. | last6 = Fine | first6 = SW. | last7 = Gopalan | first7 = A. | last8 = Reuter | first8 = VE. | last9 = Rosenblum | first9 = MK. | title = Clear-cell papillary renal cell carcinoma: molecular and immunohistochemical analysis with emphasis on the von Hippel-Lindau gene and hypoxia-inducible factor pathway-related proteins. | journal = Mod Pathol | volume = 24 | issue = 9 | pages = 1207-20 | month = Sep | year = 2011 | doi = 10.1038/modpathol.2011.80 | PMID = 21602815 }}</ref> abbreviated '''CCTPRCC'''.
It was also previously known as '''clear cell tubulopapillary renal cell carcinoma''',<ref name=pmid21602815>{{Cite journal  | last1 = Rohan | first1 = SM. | last2 = Xiao | first2 = Y. | last3 = Liang | first3 = Y. | last4 = Dudas | first4 = ME. | last5 = Al-Ahmadie | first5 = HA. | last6 = Fine | first6 = SW. | last7 = Gopalan | first7 = A. | last8 = Reuter | first8 = VE. | last9 = Rosenblum | first9 = MK. | title = Clear-cell papillary renal cell carcinoma: molecular and immunohistochemical analysis with emphasis on the von Hippel-Lindau gene and hypoxia-inducible factor pathway-related proteins. | journal = Mod Pathol | volume = 24 | issue = 9 | pages = 1207-20 | month = Sep | year = 2011 | doi = 10.1038/modpathol.2011.80 | PMID = 21602815 }}</ref> abbreviated '''CCTPRCC'''.


==General==
==General==
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<pre>
<pre>
A. Left Kidney Mass, Radical Nephrectomy:
A. Left Kidney Mass, Radical Nephrectomy:
- CLEAR CELL PAPILLARY RENAL CELL TUMOUR, nucleolar grade 1 of 4, see comment.
    - CLEAR CELL PAPILLARY RENAL CELL TUMOUR, nucleolar grade 1 of 4, see comment.
     -- Margins clear.
     -- Margins clear.
     -- Please see synoptic report.
     -- Please see synoptic report.
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NEGATIVE: CD10, AMACR.
NEGATIVE: CD10, AMACR.


The findings are in keeping with clear cell papillary renal cell tumour. These tumours were previously called "clear cell papillary renal cell carcinoma".
The findings are in keeping with clear cell papillary renal cell tumour. These tumours were previously called "clear cell papillary renal cell carcinoma".[1]


These tumours have a highly favourable clinical behaviour.[1,2]  
These tumours have a highly favourable clinical behaviour.[2,3]  


1. Am J Surg Pathol. 2015 Dec;39(12):1621-34. DOI: 10.1097/PAS.0000000000000513
1. Pathologica. 2022 Feb;115(1):8-22. doi: 10.32074/1591-951X-818. https://pmc.ncbi.nlm.nih.gov/articles/PMC10342217/
2. Pathology. 2020 Nov 19;S0031-3025(20)30957-0. DOI: 10.1016/j.pathol.2020.10.002
2. Am J Surg Pathol. 2015 Dec;39(12):1621-34. DOI: 10.1097/PAS.0000000000000513
3. Pathology. 2020 Nov 19;S0031-3025(20)30957-0. DOI: 10.1016/j.pathol.2020.10.002
</pre>
</pre>


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