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Difference between revisions of "Male infertility"
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→Hypospematogensis: fix sp
(ITGCN --> GCNIS) |
(→Hypospematogensis: fix sp) |
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*Infertility is a [[clinical diagnosis]]. | *Infertility is a [[clinical diagnosis]]. | ||
It can be divided into:<ref name=pmid20670143>{{ | It can be divided into:<ref name=pmid20670143>{{cite journal |authors=Cerilli LA, Kuang W, Rogers D |title=A practical approach to testicular biopsy interpretation for male infertility |journal=Arch Pathol Lab Med |volume=134 |issue=8 |pages=1197–204 |date=August 2010 |pmid=20670143 |doi=10.5858/2009-0379-RA.1 |url=}}</ref> | ||
*Pre-testicular - e.g. hormonal, [[pituitary gland|pituitary]]. | *Pre-testicular - e.g. hormonal, [[pituitary gland|pituitary]]. | ||
*Testicular. | *Testicular. | ||
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===Mixed pattern=== | ===Mixed pattern=== | ||
<pre> | <pre> | ||
LEFT TESTIS, BIOPSY | LEFT TESTIS, BIOPSY WITH SPERM RETRIEVAL: | ||
- SERTOLI CELLS ONLY REGIONS (25% OF BIOPSY) | - SERTOLI CELLS ONLY REGIONS (25% OF BIOPSY) INTERMIXED WITH | ||
HISTOLOGICALLY NORMAL TESTIS (75% OF BIOPSY) WITH NORMAL NUMBERS | HISTOLOGICALLY NORMAL TESTIS (75% OF BIOPSY) WITH NORMAL NUMBERS | ||
OF SPERM. | OF SPERM. | ||
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- NEGATIVE FOR SIGNIFICANT INFLAMMATION. | - NEGATIVE FOR SIGNIFICANT INFLAMMATION. | ||
- NEGATIVE FOR GERM CELL NEOPLASIA IN SITU (INTRATUBULAR GERM CELL NEOPLASIA). | - NEGATIVE FOR GERM CELL NEOPLASIA IN SITU (INTRATUBULAR GERM CELL NEOPLASIA). | ||
</pre> | |||
===Hypospematogensis=== | |||
<pre> | |||
A. Left Testis, Biopsy with Sperm Retrieval: | |||
- Hypospematogensis (70% of biopsy) intermixed with histologically normal | |||
test (30% of biopsy) with normal numbers of sperm. | |||
- NEGATIVE for significant seminiferous tubule hyalinization. | |||
- NEGATIVE for significant inflammation. | |||
- NEGATIVE for germ cell neoplasia in situ. | |||
</pre> | |||
===Normal=== | |||
<pre> | |||
A. Right Testis, Biopsy: | |||
- Testis within normal limits with spermatogenesis. | |||
- NEGATIVE for significant inter-tubular changes. | |||
- NEGATIVE for significant seminiferous tubule hyalinization. | |||
- NEGATIVE for significant inflammation. | |||
- NEGATIVE for germ cell neoplasia in situ. | |||
</pre> | </pre> | ||