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Difference between revisions of "Salivary glands"
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m
→Adenoid cystic carcinoma
m (→Adenoid cystic carcinoma: wikify) |
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*Cribriform architecture (classic). | *Cribriform architecture (classic). | ||
**Others: solid, cords, (bilayered) tubules. | **Others: solid, cords, (bilayered) tubules. | ||
**Cystic spaces filled with eosinophilic material (that is PAS +ve).<ref name=pc_add>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970070-5 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970070-5]. Accessed on: 12 May 2011.</ref> | |||
*Scant cytoplasm - eosinophilic to clear. | *Scant cytoplasm - eosinophilic to clear. | ||
*Nucleus - "bland" (small). | *Nucleus - "bland" (small). | ||
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*High grade = solid component >=30% | *High grade = solid component >=30% | ||
=== | ===Stains=== | ||
Special stains: | |||
*PAS +ve material - cystic spaces.<ref name=pc_add>URL: [http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970070-5 http://www.pathconsultddx.com/pathCon/diagnosis?pii=S1559-8675%2806%2970070-5]. Accessed on: 12 May 2011.</ref> | |||
IHC:<ref name=pmid19360297>{{Cite journal | last1 = Sequeiros-Santiago | first1 = G. | last2 = García-Carracedo | first2 = D. | last3 = Fresno | first3 = MF. | last4 = Suarez | first4 = C. | last5 = Rodrigo | first5 = JP. | last6 = Gonzalez | first6 = MV. | title = Oncogene amplification pattern in adenoid cystic carcinoma of the salivary glands. | journal = Oncol Rep | volume = 21 | issue = 5 | pages = 1215-22 | month = May | year = 2009 | doi = | PMID = 19360297 }}</ref> | |||
*CD117 +ve. | *CD117 +ve. | ||
*Cyclin D1 +ve. | *Cyclin D1 +ve. | ||