Difference between revisions of "Syringoma"

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#redirect [[Dermatologic_neoplasms#Syringoma]]
{{ Infobox diagnosis
| Name      = {{PAGENAME}}
| Image      = Syringoma -- low mag.jpg
| Width      =
| Caption    = Syringoma. [[H&E stain]]. (WC)
| Synonyms  =
| Micro      = bilayered cytologically bland ducts with tadpole-like appearance
| Subtypes  =
| LMDDx      =
| Stains    =
| IHC        =
| EM        =
| Molecular  =
| IF        =
| Gross      = usually lower eyelid lesion
| Grossing  = [[unoriented skin ellipse grossing]], [[oriented skin ellipse grossing]]
| Staging    =
| Site      = [[skin]], [[eyelid]] - see ''[[dermatologic neoplasms]]''
| Assdx      =
| Syndromes  =
| Clinicalhx = classically female
| Signs      =
| Symptoms  =
| Prevalence =
| Bloodwork  =
| Rads      =
| Endoscopy  =
| Prognosis  = benign
| Other      =
| ClinDDx    =
| Tx        =
}}
'''Syringoma''' is a benign skin lesion.
 
==General==
*Benign sweat duct tumour.
*Eccrine differentiation.
*Classically lower [[eyelid]].<ref>{{Ref PBoD8|1177}}</ref><ref name=pmid17326243/>
*Typical female - female:male = 6.6:1.<ref name=pmid17326243>{{cite journal |authors=Lee JH, Chang JY, Lee KH |title=Syringoma: a clinicopathologic and immunohistologic study and results of treatment |journal=Yonsei Med J |volume=48 |issue=1 |pages=35–40 |date=February 2007 |pmid=17326243 |pmc=2628001 |doi=10.3349/ymj.2007.48.1.35 |url=}}</ref>
 
==Microscopic==
Features:<ref>URL: [http://emedicine.medscape.com/article/1059871-diagnosis http://emedicine.medscape.com/article/1059871-diagnosis]. Accessed on: 12 May 2010.</ref>
*Proliferation of benign ducts with lined by a bilayer (as in normal sweat ducts) with abnormal architecture:
**Tadpole like appearing ducts.
 
DDx:
*Syringomatous adenomas of nipple (AKA syringoma of the nipple).<ref name=pmid22355740>{{Cite journal  | last1 = Boecker | first1 = W. | last2 = Junkers | first2 = T. | last3 = Reusch | first3 = M. | last4 = Buerger | first4 = H. | last5 = Korsching | first5 = E. | last6 = Metze | first6 = D. | last7 = Decker | first7 = T. | last8 = Loening | first8 = T. | last9 = Lange | first9 = A. | title = Origin and differentiation of breast nipple syringoma. | journal = Sci Rep | volume = 2 | issue =  | pages = 226 | month =  | year = 2012 | doi = 10.1038/srep00226 | PMID = 22355740 |URL = http://www.nature.com/srep/2012/120117/srep00226/full/srep00226.html }}</ref>
*[[Chondroid syringoma]]. (???)
 
===Images===
<gallery>
Image: Syringoma -- very low mag.jpg | Syringoma - very low  mag.
Image: Syringoma -- low mag.jpg | Syringoma - low  mag.
Image: Syringoma -- intermed mag.jpg | Syringoma - intermed.  mag.
Image: Syringoma - alt -- intermed mag.jpg | Syringoma - intermed.  mag.
Image: Syringoma -- high mag.jpg | Syringoma - high  mag.
</gallery>
<gallery>
Image: SkinTumors-P8080545.JPG | Syringoma
</gallery>
*[http://www.flickr.com/photos/euthman/2329061316/ Syringoma (flickr.com)].
*[http://dermatology.cdlib.org/144/tumors/axillary_syringoma/2.jpg Syringoma (dermatology.cdlib.org)].<ref>{{Cite journal  | last1 = Nosrati | first1 = N. | last2 = Coleman | first2 = NM. | last3 = Hsu | first3 = S. | title = Axillary syringomas. | journal = Dermatol Online J | volume = 14 | issue = 4 | pages = 13 | month =  | year = 2008 | doi =  | PMID = 18627735 |URL = http://dermatology.cdlib.org/144/tumors/axillary_syringoma/hsu.html}}</ref>
 
==Sign out==
<pre>
A. Right Lower Eyelid Lesion, Biopsy:
- Benign syringoma.
</pre>
 
==See also==
*[[Dermatologic neoplasms]].
*[[Chondroid syringoma]].
 
==References==
{{Reflist|2}}
 
[[Category:Diagnosis]]
[[Category:Dermatopathology]]

Latest revision as of 04:10, 1 November 2024

Syringoma
Diagnosis in short

Syringoma. H&E stain. (WC)
LM bilayered cytologically bland ducts with tadpole-like appearance
Gross usually lower eyelid lesion
Grossing notes unoriented skin ellipse grossing, oriented skin ellipse grossing
Site skin, eyelid - see dermatologic neoplasms
Clinical history classically female
Prognosis benign

Syringoma is a benign skin lesion.

General

  • Benign sweat duct tumour.
  • Eccrine differentiation.
  • Classically lower eyelid.[1][2]
  • Typical female - female:male = 6.6:1.[2]

Microscopic

Features:[3]

  • Proliferation of benign ducts with lined by a bilayer (as in normal sweat ducts) with abnormal architecture:
    • Tadpole like appearing ducts.

DDx:

Images

  • Syringoma - very low mag.

  • Syringoma - low mag.

  • Syringoma - intermed. mag.

  • Syringoma - intermed. mag.

  • Syringoma - high mag.

  • Syringoma

Sign out

A. Right Lower Eyelid Lesion, Biopsy:
	- Benign syringoma.

See also

References

  1. ↑ Kumar, Vinay; Abbas, Abul K.; Fausto, Nelson; Aster, Jon (2009). Robbins and Cotran pathologic basis of disease (8th ed.). Elsevier Saunders. pp. 1177. ISBN 978-1416031215.
  2. ↑ 2.0 2.1 Lee JH, Chang JY, Lee KH (February 2007). "Syringoma: a clinicopathologic and immunohistologic study and results of treatment". Yonsei Med J 48 (1): 35–40. doi:10.3349/ymj.2007.48.1.35. PMC 2628001. PMID 17326243. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628001/.
  3. ↑ URL: http://emedicine.medscape.com/article/1059871-diagnosis. Accessed on: 12 May 2010.
  4. ↑ Boecker, W.; Junkers, T.; Reusch, M.; Buerger, H.; Korsching, E.; Metze, D.; Decker, T.; Loening, T. et al. (2012). "Origin and differentiation of breast nipple syringoma.". Sci Rep 2: 226. doi:10.1038/srep00226. PMID 22355740.
  5. ↑ Nosrati, N.; Coleman, NM.; Hsu, S. (2008). "Axillary syringomas.". Dermatol Online J 14 (4): 13. PMID 18627735.
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