Difference between revisions of "Amyloid in the seminal vesicles"
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[[Image:Seminal vesicles with amyloid -- low mag.jpg|right|thumb|Seminal vesicle with amyloid. [[H&E stain]].]] | |||
'''Amyloid in the seminal vesicles''' is a relatively common histologic finding. | '''Amyloid in the seminal vesicles''' is a relatively common histologic finding. | ||
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===Significance/management=== | ===Significance/management=== | ||
*A paper by Yang ''et al.'' (looking at a small series) suggests seminal vesicle amyloid is not necessary to work-up further.<ref name=pmid23223033>{{Cite journal | last1 = Yang | first1 = Z. | last2 = Laird | first2 = A. | last3 = Monaghan | first3 = A. | last4 = Seywright | first4 = M. | last5 = Ahmad | first5 = I. | last6 = Leung | first6 = HY. | title = Incidental seminal vesicle amyloidosis observed in diagnostic prostate biopsies--are routine investigations for systemic amyloidosis warranted? | journal = Asian J Androl | volume = 15 | issue = 1 | pages = 149-51 | month = Jan | year = 2013 | doi = 10.1038/aja.2012.125 | PMID = 23223033 }}</ref> | *A paper by Yang ''et al.'' (looking at a small series) suggests seminal vesicle amyloid is ''not'' necessary to work-up further.<ref name=pmid23223033>{{Cite journal | last1 = Yang | first1 = Z. | last2 = Laird | first2 = A. | last3 = Monaghan | first3 = A. | last4 = Seywright | first4 = M. | last5 = Ahmad | first5 = I. | last6 = Leung | first6 = HY. | title = Incidental seminal vesicle amyloidosis observed in diagnostic prostate biopsies--are routine investigations for systemic amyloidosis warranted? | journal = Asian J Androl | volume = 15 | issue = 1 | pages = 149-51 | month = Jan | year = 2013 | doi = 10.1038/aja.2012.125 | PMID = 23223033 }}</ref> | ||
Note: | Note: | ||
*Amyloid in the prostate is rare and should be worked-up.<ref name=pmid32961226>{{cite journal |authors=Nevo A, Muchtar E, Stern KL, Moore JP, Cheney SM, Humphreys MR, Grogan M, Stanton ML |title=The Clinical Implication of Incidental Prostatic Amyloidosis |journal=Urology |volume=145 |issue= |pages=253–257 |date=November 2020 |pmid=32961226 |doi=10.1016/j.urology.2020.08.053 |url=}}</ref> | *Amyloid in the prostate is rare and ''should'' be worked-up.<ref name=pmid32961226>{{cite journal |authors=Nevo A, Muchtar E, Stern KL, Moore JP, Cheney SM, Humphreys MR, Grogan M, Stanton ML |title=The Clinical Implication of Incidental Prostatic Amyloidosis |journal=Urology |volume=145 |issue= |pages=253–257 |date=November 2020 |pmid=32961226 |doi=10.1016/j.urology.2020.08.053 |url=}}</ref> | ||
==Microscopic== | |||
Features: | |||
*Hyaline material with a "cracked" appearance surrounding the glandular component of the seminal vesicles. | |||
===Images=== | |||
<gallery> | |||
Image: Seminal vesicles with amyloid -- very low mag.jpg | SV with amyloid - very low mag. | |||
Image: Seminal vesicles with amyloid -- low mag.jpg | SV with amyloid - low mag. | |||
Image: Seminal vesicles with amyloid -- intermed mag.jpg | SV with amyloid - intermed. mag. | |||
Image: Seminal vesicles with amyloid -- high mag.jpg | SV with amyloid - high mag. | |||
Image: Seminal vesicles with amyloid -- very high mag.jpg | SV with amyloid - very high mag. | |||
</gallery> | |||
==Stains== | ==Stains== | ||
*[[Congo red]] +ve. | *[[Congo red]] +ve. | ||
===Images=== | |||
<gallery> | |||
Image: Seminal vesicles with amyloid - congo red -- low mag.jpg | SV with amyloid - congo red - low mag. | |||
Image: Seminal vesicles with amyloid - congo red -- intermed mag.jpg | SV with amyloid - congo red - intermed. mag. | |||
</gallery> | |||
==See also== | ==See also== | ||
Latest revision as of 03:23, 1 November 2024
Seminal vesicle with amyloid. H&E stain.
Amyloid in the seminal vesicles is a relatively common histologic finding.
General
Significance/management
- A paper by Yang et al. (looking at a small series) suggests seminal vesicle amyloid is not necessary to work-up further.[3]
Note:
- Amyloid in the prostate is rare and should be worked-up.[4]
Microscopic
Features:
- Hyaline material with a "cracked" appearance surrounding the glandular component of the seminal vesicles.
Images
SV with amyloid - very low mag.
SV with amyloid - low mag.
SV with amyloid - intermed. mag.
SV with amyloid - high mag.
SV with amyloid - very high mag.
Stains
- Congo red +ve.
Images
SV with amyloid - congo red - low mag.
SV with amyloid - congo red - intermed. mag.
See also
References
- ↑ Argon, A.; Sımşır, A.; Sarsik, B.; Tuna, B.; Yörükoğlu, K.; Nıflıoğlu, GG.; Sen, S. (2012). "Amyloidosis of seminal vesicles; incidence and pathologic characteristics.". Turk Patoloji Derg 28 (1): 44-8. doi:10.5146/tjpath.2012.01096. PMID 22207431.
- ↑ Pitkänen, P.; Westermark, P.; Cornwell, GG.; Murdoch, W. (Jan 1983). "Amyloid of the seminal vesicles. A distinctive and common localized form of senile amyloidosis.". Am J Pathol 110 (1): 64-9. PMID 6849372.
- ↑ Yang, Z.; Laird, A.; Monaghan, A.; Seywright, M.; Ahmad, I.; Leung, HY. (Jan 2013). "Incidental seminal vesicle amyloidosis observed in diagnostic prostate biopsies--are routine investigations for systemic amyloidosis warranted?". Asian J Androl 15 (1): 149-51. doi:10.1038/aja.2012.125. PMID 23223033.
- ↑ Nevo A, Muchtar E, Stern KL, Moore JP, Cheney SM, Humphreys MR, Grogan M, Stanton ML (November 2020). "The Clinical Implication of Incidental Prostatic Amyloidosis". Urology 145: 253–257. doi:10.1016/j.urology.2020.08.053. PMID 32961226.