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Difference between revisions of "Cowper gland adenocarcinoma"
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'''Cowper gland adenocarcinoma''' is a [[cancer]] of the [[bulbourethral gland]]. | '''Cowper gland adenocarcinoma''', also '''bulbourethral gland adenocarcinoma''', is a [[cancer]] of the [[bulbourethral gland]]. It is very rare. | ||
==General== | ==General== | ||
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==Microscopic== | ==Microscopic== | ||
Features:<ref name=WHOGU2022_187/><ref name=pmid1311394>{{cite journal |authors=Small JD, Albertsen PC, Graydon RJ, Ricci A, Sardella WV |title=Adenoid cystic carcinoma of Cowper's gland |journal=J Urol |volume=147 |issue=3 |pages=699–701 |date=March 1992 |pmid=1311394 |doi=10.1016/s0022-5347(17)37357-3 |url=}}</ref> | Features:<ref name=WHOGU2022_187/><ref name=pmid1311394>{{cite journal |authors=Small JD, Albertsen PC, Graydon RJ, Ricci A, Sardella WV |title=Adenoid cystic carcinoma of Cowper's gland |journal=J Urol |volume=147 |issue=3 |pages=699–701 |date=March 1992 |pmid=1311394 |doi=10.1016/s0022-5347(17)37357-3 |url=}}</ref> | ||
*Cribriform or trabecular or solid pattern. | *Cribriform ‡ or trabecular or solid pattern. | ||
*Cytologically bland morphology. | *Cytologically bland morphology. | ||
Note: | |||
*‡ May have morphology of ''[[adenoid cystic carcinoma]]'' and have MYB-NFIB fusion.<ref name=WHOGU2022_187/><ref>{{cite journal |authors=Myers CE, Gatalica Z, Spinelli A, Castro M, Linden E, Sartor O, Sargent M |title=Metastatic Cancer of Cowper's Gland: A Rare Cancer Managed Successfully by Molecular Profiling |journal=Case Rep Oncol |volume=7 |issue=1 |pages=52–7 |date=January 2014 |pmid=24575017 |pmc=3934673 |doi=10.1159/000357972 |url=}}</ref> | |||
DDx: | DDx: | ||
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*SMA -ve. | *SMA -ve. | ||
*S-100 -ve. | *S-100 -ve. | ||
Note: Benign Cowper's glands are described as PSA +ve, PSAP -ve, HMWK +ve.<ref name=pmid9158679>{{Cite journal | last1 = Cina | first1 = SJ. | last2 = Silberman | first2 = MA. | last3 = Kahane | first3 = H. | last4 = Epstein | first4 = JI. | title = Diagnosis of Cowper's glands on prostate needle biopsy. | journal = Am J Surg Pathol | volume = 21 | issue = 5 | pages = 550-5 | month = May | year = 1997 | doi = | PMID = 9158679 }}</ref> | |||
==See also== | ==See also== | ||