Difference between revisions of "Cowper gland adenocarcinoma"
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==Microscopic== | ==Microscopic== | ||
Features:<ref name=WHOGU2022_187/><ref name=pmid1311394>{{cite journal |authors=Small JD, Albertsen PC, Graydon RJ, Ricci A, Sardella WV |title=Adenoid cystic carcinoma of Cowper's gland |journal=J Urol |volume=147 |issue=3 |pages=699–701 |date=March 1992 |pmid=1311394 |doi=10.1016/s0022-5347(17)37357-3 |url=}}</ref> | Features:<ref name=WHOGU2022_187/><ref name=pmid1311394>{{cite journal |authors=Small JD, Albertsen PC, Graydon RJ, Ricci A, Sardella WV |title=Adenoid cystic carcinoma of Cowper's gland |journal=J Urol |volume=147 |issue=3 |pages=699–701 |date=March 1992 |pmid=1311394 |doi=10.1016/s0022-5347(17)37357-3 |url=}}</ref> | ||
* | *Cribriform‡ or trabecular or solid pattern. | ||
*Cytologically bland morphology. | *Cytologically bland morphology. | ||
Note: | |||
*‡ May have morphology of ''[[adenoid cystic carcinoma]]'' and have MYB-NFIB fusion.<ref name=WHOGU2022_187/> | |||
DDx: | DDx: | ||
Revision as of 21:54, 18 June 2024
Cowper gland adenocarcinoma, also bulbourethral gland adenocarcinoma, is a cancer of the bulbourethral gland. It is very rare.
General
- Extremely rare - 9 reported cases in 2016.[1]
Microscopic
- Cribriform‡ or trabecular or solid pattern.
- Cytologically bland morphology.
Note:
- ‡ May have morphology of adenoid cystic carcinoma and have MYB-NFIB fusion.[2]
DDx:
IHC
Features:[2]
- CK7 +ve.
- HWCK +ve.
- PSA -ve.
- PSAP -ve.
- SMA -ve.
- S-100 -ve.
See also
References
- ↑ Zhang M, Pettaway C, Vikram R, Tamboli P (December 2016). "Adenoid cystic carcinoma of the urethra/Cowper's gland with concurrent high-grade prostatic adenocarcinoma: a detailed clinicopathologic case report and review of the literature". Hum Pathol 58: 138–144. doi:10.1016/j.humpath.2016.07.027. PMID 27554206.
- ↑ 2.0 2.1 2.2 WHO Classification of Tumours Editorial Board (2022). Urinary and Male Genital Tumours (5th ed.). Lyon: World Health Organization. pp. 187. ISBN 978-9283245124.
- ↑ Small JD, Albertsen PC, Graydon RJ, Ricci A, Sardella WV (March 1992). "Adenoid cystic carcinoma of Cowper's gland". J Urol 147 (3): 699–701. doi:10.1016/s0022-5347(17)37357-3. PMID 1311394.