Difference between revisions of "Cowper gland adenocarcinoma"

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'''Cowper gland adenocarcinoma''' is a [[cancer]] of the [bulbourethral gland]].
'''Cowper gland adenocarcinoma''' is a [[cancer]] of the [[bulbourethral gland]].


==General==
*Extremely rare - 9 reported cases in 2016.<ref>{{cite journal |authors=Zhang M, Pettaway C, Vikram R, Tamboli P |title=Adenoid cystic carcinoma of the urethra/Cowper's gland with concurrent high-grade prostatic adenocarcinoma: a detailed clinicopathologic case report and review of the literature |journal=Hum Pathol |volume=58 |issue= |pages=138–144 |date=December 2016 |pmid=27554206 |doi=10.1016/j.humpath.2016.07.027 |url=}}</ref>
==Microscopic==
Features:<ref name=pmid1311394>{{cite journal |authors=Small JD, Albertsen PC, Graydon RJ, Ricci A, Sardella WV |title=Adenoid cystic carcinoma of Cowper's gland |journal=J Urol |volume=147 |issue=3 |pages=699–701 |date=March 1992 |pmid=1311394 |doi=10.1016/s0022-5347(17)37357-3 |url=}}</ref>
*Cribriform or trabecular or solid pattern.
*Cytologically bland morphology.
DDx:
*[[Urothelial carcinoma]].
*[[Prostatic adenocarcinoma]].
*[[Clear cell adenocarcinoma of the urethra]].
==IHC==
Features:<ref>WHO Blue Book - Page 187.</ref>
*CK7 +ve.
*HWCK +ve.
*PSA -ve.
*PSAP -ve.
*SMA -ve.
*S-100 -ve.
==See also==
*[[Bulbourethral gland]].
==References==
{{Reflist|1}}


[[Category:Diagnosis]]
[[Category:Diagnosis]]

Revision as of 21:31, 18 June 2024

Cowper gland adenocarcinoma is a cancer of the bulbourethral gland.

General

  • Extremely rare - 9 reported cases in 2016.[1]

Microscopic

Features:[2]

  • Cribriform or trabecular or solid pattern.
  • Cytologically bland morphology.

DDx:

IHC

Features:[3]

  • CK7 +ve.
  • HWCK +ve.
  • PSA -ve.
  • PSAP -ve.
  • SMA -ve.
  • S-100 -ve.

See also

References

  1. Zhang M, Pettaway C, Vikram R, Tamboli P (December 2016). "Adenoid cystic carcinoma of the urethra/Cowper's gland with concurrent high-grade prostatic adenocarcinoma: a detailed clinicopathologic case report and review of the literature". Hum Pathol 58: 138–144. doi:10.1016/j.humpath.2016.07.027. PMID 27554206.
  2. Small JD, Albertsen PC, Graydon RJ, Ricci A, Sardella WV (March 1992). "Adenoid cystic carcinoma of Cowper's gland". J Urol 147 (3): 699–701. doi:10.1016/s0022-5347(17)37357-3. PMID 1311394.
  3. WHO Blue Book - Page 187.